From GH to Billy Ghrelin

被引：2
|
作者：
Smith, Roy G. [1 ]
机构：
[1] Scripps Res Inst Florida, Dept Metab & Aging, Jupiter, FL 33458 USA
来源：
CELL METABOLISM | 2009年 / 10卷 / 02期
关键词：
ENERGY-BALANCE; SECRETION; HORMONE; PEPTIDE;
D O I：
10.1016/j.cmet.2009.07.009
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The octanoylated peptide hormone ghrelin regulates episodic growth hormone release and energy balance. Work in genetically modified mice (Kirchner et al., 2009) now shows that in vivo activity of ghrelin O-acyltransferase (GOAT), responsible for ghrelin octanoylation, decreases during fasting but increases after ingesting medium-chain fatty acid triglycerides (MCT).
引用
收藏
页码：82 / 83
页数：2
相关论文
共 50 条
  • [21] Acylated ghrelin as a provocative test for the diagnosis of GH deficiency in adults
    Gasco, Valentina
    Beccuti, Guglielmo
    Baldini, Chiara
    Prencipe, Nunzia
    Di Giacomo, Stellina
    Berton, Alessandro
    Guaraldi, Federica
    Tabaro, Isabella
    Maccario, Mauro
    Ghigo, Ezio
    Grottoli, Silvia
    EUROPEAN JOURNAL OF ENDOCRINOLOGY, 2013, 168 (01) : 23 - 30
  • [22] Rapid desensitisation of the GH secretagogue (ghrelin) receptor to hexarelin in vitro
    Orkin, RD
    New, DI
    Norman, D
    Chew, SL
    Clark, AJL
    Grossman, AB
    Korbonits, M
    JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, 2003, 26 (08) : 743 - 747
  • [23] The role of pituitary ghrelin in growth hormone (GH) secretion: GH-releasing hormone-dependent regulation of pituitary ghrelin gene expression and peptide content
    Kamegai, J
    Tamura, H
    Shimizu, T
    Ishii, S
    Tatsuguchi, A
    Sugihara, H
    Oikawa, S
    Kineman, RD
    ENDOCRINOLOGY, 2004, 145 (08) : 3731 - 3738
  • [24] Lights! Camera! Arkansas!: From Broncho Billy to Billy Bob Thornton
    Cullum, Paul
    ARKANSAS HISTORICAL QUARTERLY, 2016, 75 (01): : 75 - 79
  • [25] Excerpts from "Billy Elliot"
    英语学习, 2001, (09) : 32 - 32
  • [26] The GH-releasing effect of ghrelin, a natural GH secretagogue, is only blunted by the infusion of exogenous somatostatin in humans
    Di Vito, L
    Broglio, F
    Benso, A
    Gottero, C
    Prodam, F
    Papotti, M
    Muccioli, G
    Dieguez, C
    Casanueva, FF
    Deghenghi, R
    Ghigo, E
    Arvat, E
    CLINICAL ENDOCRINOLOGY, 2002, 56 (05) : 643 - 648
  • [27] Ghrelin: A GH-Releasing, Appetite-Regulating Gastric Hormone
    Di Michele, Joseph
    Rotondo, Fabio
    Kovacs, Kalman
    Di Ieva, Antonio
    Syro, Luis V.
    Latta, Eleanor
    Cusimano, Michael D.
    ADVANCES IN NEUROIMMUNE BIOLOGY, 2013, 4 (02) : 51 - 65
  • [28] Ghrelin stimulates GH but not food intake in arcuate nucleus ablated rats
    Tamura, H
    Kamegai, J
    Shimizu, T
    Ishii, S
    Sugihara, H
    Oikawa, S
    ENDOCRINOLOGY, 2002, 143 (09) : 3268 - 3275
  • [29] Ghrelin test for the assessment of GH status in successfully treated patients with acromegaly
    Pekic, S.
    Doknic, M.
    Miljic, D.
    Joksimovic, M.
    Glodic, J.
    Djurovic, M.
    Dieguez, C.
    Casanueva, F.
    Popovic, V.
    EUROPEAN JOURNAL OF ENDOCRINOLOGY, 2006, 154 (05) : 659 - 666
  • [30] Primary hyperparathyroidism is associated with marked impairment of GH response to acylated ghrelin
    Cecconi, E.
    Bogazzi, F.
    Morselli, L. L.
    Gasperi, M.
    Procopio, M.
    Gramaglia, E.
    Broglio, F.
    Giovannetti, C.
    Ghigo, E.
    Martino, E.
    CLINICAL ENDOCRINOLOGY, 2008, 69 (02) : 197 - 201
12345