The application of genome-wide SNP genotyping methods in studies on livestock genomes

被引:25
|
作者
Gurgul, Artur [1 ]
Semik, Ewelina [1 ]
Pawlina, Klaudia [1 ]
Szmatoa, Tomasz [1 ]
Jasielczuk, Igor [1 ]
Bugno-Poniewierska, Monika [1 ]
机构
[1] Natl Res Inst Anim Prod, Lab Genom, PL-32083 Balice, Poland
关键词
Copy number variation; Genetic differentiation; Linkage disequilibrium; Runs of homozygosity; Selection signatures; COPY-NUMBER VARIATION; EFFECTIVE POPULATION-SIZE; COMMON DELETION POLYMORPHISMS; LINKAGE DISEQUILIBRIUM MAPS; HAPLOTYPE BLOCK STRUCTURE; POSITIVE SELECTION; DAIRY-CATTLE; STRUCTURAL VARIATION; BREED ASSIGNMENT; JAPANESE BLACK;
D O I
10.1007/s13353-014-0202-4
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Animal genomics is currently undergoing dynamic development, which is driven by the flourishing of high-throughput genome analysis methods. Recently, a large number of animals has been genotyped with the use of whole-genome genotyping assays in the course of genomic selection programmes. The results of such genotyping can also be used for studies on different aspects of livestock genome functioning and diversity. In this article, we review the recent literature concentrating on various aspects of animal genomics, including studies on linkage disequilibrium, runs of homozygosity, selection signatures, copy number variation and genetic differentiation of animal populations. Our work is aimed at providing insight into certain achievements of animal genomics and to arouse interest in basic research on the complexity and structure of the genomes of livestock.
引用
收藏
页码:197 / 208
页数:12
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