Current aspects of pulmonary arterial hypertension and therapeutics

被引:0
|
作者
Li, Xianchi [1 ]
Liu, Yuanyuang [1 ]
Zhang, Peiying [1 ]
机构
[1] Xuzhou Cent Hosp, Xuzhou, Peoples R China
来源
MINERVA CARDIOANGIOLOGICA | 2017年 / 65卷 / 02期
关键词
Hypertension; pulmonary; Therapeutics; Adrenergic beta-antagonists; RIGHT-VENTRICULAR FUNCTION; CALCIUM-CHANNEL BLOCKERS; LONG-TERM RESPONSE; SIGNALING CONTRIBUTES; AEROBIC EXERCISE; SURVIVAL; PROSTACYCLIN; MANAGEMENT; PHYSIOLOGY; DISEASE;
D O I
10.23736/S0026-4725.16.04266-3
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The pulmonary arterial hypertension (PAH) patients have high rate of mortality due to right ventricle (or ventricular) (RV) failures. A lot of research work is being carried out in the area, however no treatment is available that could contrast the rise in mortality rates in PAH patients. beta 1-adrenoceptor blockers (beta-blockers, BB) reduced mortality in left heart failure, but they do not explored much at clinical level. Recent studies suggest beta-blockers might be beneficial in PAH; however the mechanisms remain unknown. The present review article would put light on all these aspects of PAH along with latest ways for the management of PAH.
引用
收藏
页码:173 / 178
页数:6
相关论文
共 50 条
  • [21] Pulmonary arterial hypertension: current therapeutic strategies
    Aniket Puri
    Michael D McGoon
    Sudhir S Kushwaha
    Nature Clinical Practice Cardiovascular Medicine, 2007, 4 : 319 - 329
  • [22] Current status of pulmonary arterial hypertension in Korea
    Jang, Albert Youngwoo
    Chung, Wook-Jin
    KOREAN JOURNAL OF INTERNAL MEDICINE, 2019, 34 (04): : 696 - 707
  • [23] Current and future treatments of pulmonary arterial hypertension
    Sommer, Natascha
    Ghofrani, Hossein A.
    Pak, Oleg
    Bonnet, Sebastien
    Provencher, Steve
    Sitbon, Olivier
    Rosenkranz, Stephan
    Hoeper, Marius M.
    Kiely, David G.
    BRITISH JOURNAL OF PHARMACOLOGY, 2021, 178 (01) : 6 - 30
  • [24] Current Treatment Approaches to Pulmonary Arterial Hypertension
    Provencher, Steeve
    Granton, John T.
    CANADIAN JOURNAL OF CARDIOLOGY, 2015, 31 (04) : 460 - 477
  • [25] Current medical treatment of pulmonary arterial hypertension
    Sulica, R
    Poon, M
    MOUNT SINAI JOURNAL OF MEDICINE, 2004, 71 (02): : 103 - 114
  • [26] Physiopathology of pulmonary arterial hypertension - Cellular and molecular aspects
    Perros, F
    Humbert, M
    PRESSE MEDICALE, 2005, 34 (03): : 232 - 242
  • [27] Ventricular interdependence - particular aspects in pulmonary arterial hypertension
    Gurghean, A.
    Varzaru, L.
    Bruckner, I. V.
    EUROPEAN HEART JOURNAL, 2007, 28 : 431 - 431
  • [28] Pharmacoeconomic aspects of macitentan in the therapy of pulmonary arterial hypertension
    Moisseeva, O. M.
    Rudakova, A. V.
    TERAPEVTICHESKII ARKHIV, 2017, 89 (03) : 72 - +
  • [29] Epidemiological and Clinical aspects of pulmonary arterial hypertension (PAH)
    Yahiaoui, Rachida
    Bennoui, Zakia
    Hakem, Djenette
    Amrane, Rabah
    Boughrarou, Rafika
    EUROPEAN RESPIRATORY JOURNAL, 2018, 52
  • [30] Current Aspects of Definition and Diagnosis of Pulmonary Hypertension
    Lange, T. J.
    Borst, M.
    Ewert, R.
    Halank, M.
    Klose, H.
    Leuchte, H.
    Meyer, F. J.
    Seyfarth, H. -J.
    Skowasch, D.
    Wilkens, H.
    Held, M.
    PNEUMOLOGIE, 2020, 74 (12): : 847 - 863