Long-term dynamics of blood pressure in intact and sympathectomized post-suspension rats

被引:0
|
作者
Borovik, A [1 ]
Tarasova, O [1 ]
Figourina, I [1 ]
Golubinskaya, V [1 ]
Vinogradova, O [1 ]
机构
[1] Space Biomed Ctr Training & Res, Moscow 117192, Russia
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中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
Low-frequency dynamics of mean arterial pressure (MAP) and pulse interval (PI) was studied in intact and sympathectomized rats after 2-week tail suspension. Correlation properties of long-term (f<0.8 Hz) MAP fluctuations were analyzed using R/S Hurst method. It was shown that time series of successive increments in MAP level display power-law fractal anticorrelations in wide range of time scales. After sympathectomy and/or suspension averaged Hurst exponents were more close to the value for uncorrelated random process (H=0.5), indicating deterioration of regulatory feedbacks. Besides, a decrease of coherence between MAP and PI in low-frequency range was observed after suspension in both intact and sympathectomized rats, indicating alteration of non-sympathetic cardiovascular control mechanisms.
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页码:213 / 214
页数:2
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