Synthesis of vinca alkaloids and related compounds.: 100.: Stereoselective oxidation reactions of compounds with the aspidospermane and quebrachamine ring system.: First synthesis of some alkaloids containing the epoxy ring

被引：18
|
作者：
Éles, J
Kalaus, G
Greiner, I
Kajtár-Peredy, M
Szabó, P
Keserû, GM
Szabó, L
Szántay, C
机构：
[1] Budapest Univ Technol & Econ, Dept Organ Chem, H-1111 Budapest, Hungary
[2] Gedeon Richter Chem Works Ltd, Chem Works, H-1103 Budapest, Hungary
[3] Hungarian Acad Sci, Chem Res Ctr, Inst Chem, H-1025 Budapest, Hungary
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2002年 / 67卷 / 21期
关键词：
D O I：
10.1021/jo020386r
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The first syntheses of the alkaloids (-)-mehranine (3), (+)-voaphylline/conoflorine (4), (+)-N-a-methylvoaphylline/hecubine (5), and (-)-lochnericine (2) were achieved by stereoselective epoxidation starting from (-)-tabersonine (1), through intermediates with the aspidospermane and quebrachamine skeleton.
引用
收藏
页码：7255 / 7260
页数：6
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