Integrative molecular and functional genomic analysis of chemotherapy resistant bladder cancer cell lines identifies novel mediators of therapeutic response

被引:0
|
作者
Jones, Robert T. [1 ]
Zuiverloon, Tahlita C. [2 ]
Vekony, Hedvig [1 ]
Goodspeed, Andrew [1 ]
Laajala, Teemu D. [3 ]
Joshi, Molishree [1 ]
Sempeck, Colin [1 ]
Tu, Megan [1 ]
Costello, James C. [1 ]
Theodorescu, Dan [4 ]
机构
[1] Univ Colorado, Aurora, CO USA
[2] Erasmus MC, Rotterdam, Netherlands
[3] Univ Turku, Turku, Finland
[4] Samuel Oschin Comprehens Canc Inst, Los Angeles, CA USA
关键词
D O I
10.1158/1538-7445.SABCS18-2107
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
2107
引用
收藏
页数:2
相关论文
共 50 条
  • [31] Combined Large Cell Neuroendocrine Carcinomas of the Lung: Integrative Molecular Analysis Identifies Subtypes with Potential Therapeutic Implications
    Simbolo, Michele
    Centonze, Giovanni
    Giudice, Luca
    Grillo, Federica
    Maisonneuve, Patrick
    Gkountakos, Anastasios
    Ciaparrone, Chiara
    Cattaneo, Laura
    Sabella, Giovanna
    Giugno, Rosalba
    Bossi, Paola
    Spaggiari, Paola
    Del Gobbo, Alessandro
    Ferrero, Stefano
    Mastracci, Luca
    Fabbri, Alessandra
    Filugelli, Martina
    Garzone, Giovanna
    Prinzi, Natalie
    Pusceddu, Sara
    Testi, Adele
    Monti, Valentina
    Rolli, Luigi
    Mangogna, Alessandro
    Bercich, Luisa
    Benvenuti, Mauro Roberto
    Bria, Emilio
    Pilotto, Sara
    Berruti, Alfredo
    Pastorino, Ugo
    Capella, Carlo
    Infante, Maurizio
    Milella, Michele
    Scarpa, Aldo
    Milione, Massimo
    CANCERS, 2022, 14 (19)
  • [32] Integrative multi-omics analysis of muscle-invasive bladder cancer identifies prognostic biomarkers for frontline chemotherapy and immunotherapy
    Qianxing Mo
    Roger Li
    Dennis O. Adeegbe
    Guang Peng
    Keith Syson Chan
    Communications Biology, 3
  • [33] Integrative multi-omics analysis of muscle-invasive bladder cancer identifies prognostic biomarkers for frontline chemotherapy and immunotherapy
    Mo, Qianxing
    Li, Roger
    Adeegbe, Dennis O.
    Peng, Guang
    Chan, Keith Syson
    COMMUNICATIONS BIOLOGY, 2020, 3 (01)
  • [34] Integrated digital pathology and transcriptome analysis identifies molecular mediators of T cell exclusion in ovarian cancer
    Desbois, Melanie
    Udyavar, Akshata
    Ryner, Lisa
    Kozlowski, Cleopatra
    Guan, Yinghui
    Durrbaum, Milena
    Lu, Shan
    Fortin, Jean-Philippe
    Koeppen, Hartmut
    Ziai, James
    Chang, Ching-Wei
    Lo, Amy
    Keerthivasan, Shilpa
    Plante, Marie
    Bourgon, Richard
    Bais, Carlos
    Hegde, Priti
    Daemen, Anneleen
    Turley, Shannon
    Wang, Yulei
    CANCER RESEARCH, 2019, 79 (13)
  • [35] Basonuclinl (BNC1): A novel therapeutic target in ovarian cancer identified through integrative TCGA-based functional genomic analysis
    Wu, Sherry Y.
    Unruh, Anna K.
    Bartholomeusz, Geoffrey
    Ivan, Cristina
    Pecot, Chad V.
    Rupaimoole, Rajesha
    Han, Hee-Dong
    Bottsford-Miller, Justin
    Tucker, Susan L.
    Coleman, Robert L.
    Lopez-Berestein, Gabriel
    Baggerly, Keith A.
    Sood, Anil K.
    CANCER RESEARCH, 2012, 72
  • [36] Integrative drug screening and multi-omic characterization of patient-derived bladder cancer organoids reveals novel molecular correlates of chemotherapy response
    Merrill, Nathan M.
    Kaffenberger, Samuel D.
    Bao, Liwei
    Vandecan, Nathalie
    Goo, Laura E.
    Apfel, Athena
    Cheng, Xu
    Qin, Zhaoping
    Liu, Chia-Jen
    Bankhead, Armand
    Wang, Yin
    Kathawate, Varun
    Tudrick, Lila
    Serhan, Habib
    Farah, Zackariah
    Ellimoottil, Chad
    Hafez, Khaled S.
    Herrel, Lindsey A.
    Montgomery, Jeffrey S.
    Morgan, Todd M.
    Salami, Simpa S.
    Weizer, Alon Z.
    Ulintz, Peter J.
    Day, Mark L.
    Soellner, Matthew B.
    Palmbos, Phillip L.
    Merajver, Sofia D.
    Udager, Aaron M.
    CLINICAL CANCER RESEARCH, 2024, 30 (10)
  • [37] Genomic analysis of canine cancer cell lines reveals molecular targets for comparative oncology
    Duval, D.
    Morales, M.
    Idate, R.
    Das, S.
    EUROPEAN JOURNAL OF CANCER, 2024, 211 : S10 - S11
  • [38] Molecular characterization of temsirolimus-induced response in human renal and bladder cancer cell lines
    Merseburger, Axel S.
    Kramer, Mario W.
    Tezval, Hossein
    Kuczyk, Markus
    Serth, Juergen
    JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (05)
  • [39] Genomic and Functional Analysis of Myxofibrosarcoma Identifies HGF/MET and Integrin α10 as Potential Prognostic Biomarkers and Novel Therapeutic Targets
    Lee, A. Y.
    Agaram, N. P.
    Qin, L.
    Crago, A. M.
    O'Connor, R. B.
    Socci, N. D.
    Okada, T.
    Singer, S.
    ANNALS OF SURGICAL ONCOLOGY, 2013, 20 : S6 - S7
  • [40] Integrative molecular analysis of combined small-cell lung carcinomas identifies major subtypes with different therapeutic opportunities
    Simbolo, M.
    Centonze, G.
    Ali, G.
    Garzone, G.
    Taormina, S.
    Sabella, G.
    Ciaparrone, C.
    Mafficini, A.
    Grillo, F.
    Mangogna, A.
    Volante, M.
    Mastracci, L.
    Fontanini, G.
    Pilotto, S.
    Bria, E.
    Infante, M.
    Capella, C.
    Rolli, L.
    Pastorino, U.
    Milella, M.
    Milione, M.
    Scarpa, A.
    ESMO OPEN, 2022, 7 (01)