Colesevelam: Effect on Bile Acid Synthesis or Excretion in IBS Diarrhea

被引：0
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作者：
Kessing, Richard
机构：
来源：
ZEITSCHRIFT FUR GASTROENTEROLOGIE | 2021年 / 59卷 / 02期
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D O I：
10.1055/a-1336-5551
中图分类号：
R57 [消化系及腹部疾病];
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摘要：
Bei einem Drittel der Patienten mit IBS-Durchfall (IBS-D) findet sich eine erhohte Gallensauresynthese oder -ausscheidung. Eine Studie zeigte positive Effekte auf die Darmfunktion des Ionenaustauschers Colesevelam. US-amerikanische Gastroenterologen verglichen die Auswirkungen von Colesevelam auf Symptome und Genexpressionsmuster in der Sigma-Dickdarmschleimhaut bei Gallensaure-Durchfall mit assoziiertem IBS-D mit Placebo.
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