Microwave promoted one-pot synthesis of 3-(2′-amino-3′-cyano-4′-arylpyrid-6′-yl) coumarins

被引:27
|
作者
Zhou, Jian Feng [1 ,2 ]
Gong, Gui Xia [2 ]
Zhu, Feng Xia [1 ]
Zhi, San Jun [1 ]
机构
[1] Huaiyin Teachers Coll, Dept Chem, Jiangsu Key Lab Chem Low Dimens Mat, Huaian 223300, Peoples R China
[2] Suzhou Univ, Sch Chem & Chem Engn, Key Lab Organ Synth Jiangsu Prov, Suzhou 215123, Peoples R China
关键词
3-(2 '-Amino-3 '-cyano-4 '-arylpyrid-6 '-yl) coumarin; Aromatic aldehyde; 3-Acetylcoumarin; Microwave irradiation; MULTICOMPONENT REACTIONS; INHIBITORS; DISCOVERY;
D O I
10.1016/j.cclet.2008.10.006
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A facile procedure for the synthesis of 3-(2'-amino-3'-cyano-4'-arylpyrid-6'-yl) coumarins are being reported starting from 3-acetylcoumarin, aromatic aldehydes and malononitrile. The reactions were carried out on microwave irradiation in good yield with short time and easy work-up. The structures of all the compounds have been confirmed on the basis of their analytical, IR, H-1 NMR, and mass spectral data. (C) 2008 Jian Feng Zhou. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
引用
收藏
页码:37 / 39
页数:3
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