Database of structural motifs in proteins

被引:12
|
作者
Guruprasad, K [1 ]
Prasad, MS [1 ]
Kumar, GR [1 ]
机构
[1] Ctr DNA Fingerprinting & Diagnost, Hyderabad 500076, Andhra Pradesh, India
关键词
D O I
10.1093/bioinformatics/16.4.372
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The database of structural motifs in proteins (DSMP) contains data relevant to helices, B-turns, gamma-turns, beta-hairpins, psi-loops, beta-alpha-beta motifs, beta-sheets, beta-strands and disulphide bridges extracted from all proteins in the Protein Data Bank primarily using the PROMOTIF program and implemented as a web-based network service using the SRS. The data corresponding to the structural motifs includes; sequence, position in polypeptide chain, geometry, type, unique code, keywords and resolution of crystal structure. This data is available for a representative data set of 1028 protein chains and also for all 10 213 proteins in the Protein Data Bank. The three-dimensional coordinates for all structural motifs (except sheet and disulphide bridge) are also available for the representative data set. Using features in SRS, DSMP can be queried to extract information from one or more structural motifs that may be useful for sequence-structure analysis, prediction, modelling or design.
引用
收藏
页码:372 / 375
页数:4
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