Recognition of osteopontin by rat bone marrow derived osteoblastic primary cells

被引:14
|
作者
Yabe, T [1 ]
Nemoto, A [1 ]
Uemura, T [1 ]
机构
[1] TSUKUBA RES CTR, NATL INST ADV INTERDISCIPLINARY RES, BION DESIGN GRP, IBARAKI, OSAKA 305, JAPAN
关键词
osteopontin; osteoblast;
D O I
10.1271/bbb.61.754
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
To study the role of osteopontin,,ve did cell adhesion and ALP assays of rat bone marrow osteoblastic cells (RBMO) on collagen Type I and osteopontin surfaces. The RBMO proved to adhere much more strongly to the osteopontin and to have higher ALP activity on the osteopontin, which suggests that pre-osteoblasts differentiate into osteoblasts that form bone by recognizing osteopontins.
引用
收藏
页码:754 / 756
页数:3
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