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Recognition of osteopontin by rat bone marrow derived osteoblastic primary cells
被引:14
|作者:
Yabe, T
[1
]
Nemoto, A
[1
]
Uemura, T
[1
]
机构:
[1] TSUKUBA RES CTR, NATL INST ADV INTERDISCIPLINARY RES, BION DESIGN GRP, IBARAKI, OSAKA 305, JAPAN
关键词:
osteopontin;
osteoblast;
D O I:
10.1271/bbb.61.754
中图分类号:
Q5 [生物化学];
Q7 [分子生物学];
学科分类号:
071010 ;
081704 ;
摘要:
To study the role of osteopontin,,ve did cell adhesion and ALP assays of rat bone marrow osteoblastic cells (RBMO) on collagen Type I and osteopontin surfaces. The RBMO proved to adhere much more strongly to the osteopontin and to have higher ALP activity on the osteopontin, which suggests that pre-osteoblasts differentiate into osteoblasts that form bone by recognizing osteopontins.
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页码:754 / 756
页数:3
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