Participation of mesenchymal precursor cells in wound healing on skin flap model

被引:7
|
作者
Goldberg, E. D. [1 ]
Dygai, A. M. [1 ]
Zhdanov, V. V. [1 ]
Zyuz'kov, G. N. [1 ]
Gur'yantseva, L. A. [1 ]
Pershina, O. V. [1 ]
Povet'eva, T. N. [1 ]
Stavrova, L. A. [1 ]
Khrichkova, T. Yu. [1 ]
机构
[1] Russian Acad Med Sci, Inst Pharmacol, Tomsk Res Ctr, Siberian Div, Tomsk 109801, Russia
关键词
skin flap; regeneration; regional stem cells; mesenchymal stem cells;
D O I
10.1007/s10517-006-0307-9
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
We studied the state of different pools of mesenchymal precursor cells in the bone marrow, peripheral blood, and wound surface after modeling of tissue damage by skin flap removal. The participation of regional and circulating stromal precursors in the healing of skin defect and the absence of compensatory reaction of the regeneratory process deep reserve, mesenchymal stem cells of the bone marrow, was demonstrated.
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页码:116 / 118
页数:3
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