Intraventricular Delivery and CRISPR-Cas9 Disruption of PD-1 is Required for CAR T-cell Efficacy in Glioblastoma

被引:0
|
作者
Choi, Bryan D.
Yu, Xiaoling
Nahed, Brian V.
Cahill, Daniel P.
Curry, William T.
Carter, Bob S.
Maus, Marcela V.
机构
关键词
D O I
暂无
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
823
引用
收藏
页码:286 / 286
页数:1
相关论文
共 50 条
  • [31] Enhanced CRISPR-Cas9 edited CAR-T cells through simultaneous inactivation of multiple T cell exhaustion pathways
    Sergeeva, Oksana
    Fearnley, Amber
    Chin, Shu Shien
    An, Xingyue
    Pels, Nana Adjoa
    Metzler, Kristen
    Joinville, Kyla
    Calderon, Lizet Aquino
    Abulizi, Abudukadier
    Karp, Hayden
    Rodriguez, Julio
    Matis, Louis
    Fine, Jay
    Myers, Jeremy
    CANCER RESEARCH, 2023, 83 (07)
  • [32] Gene therapy for Glaucoma by CRISPR-Cas9 mediated disruption of Aquaporin 1 in the Ciliary Body
    Chu, Colin J.
    Wu, Jiahui
    Bell, Oliver Hugh
    Copland, David
    Maswood, Ryea
    Young, Alison
    Pooley, John
    Khaw, Peng Tee
    Ali, Robin R.
    Dick, Andrew D.
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2019, 60 (09)
  • [33] Gene Therapy for Glaucoma by Ciliary Body Aquaporin 1 Disruption Using CRISPR-Cas9
    Wu, Jiahui
    Bell, Oliver H.
    Copland, David A.
    Young, Alison
    Pooley, John R.
    Maswood, Ryea
    Evans, Rachel S.
    Khaw, Peng Tee
    Ali, Robin R.
    Dick, Andrew D.
    Chu, Colin J.
    MOLECULAR THERAPY, 2020, 28 (03) : 820 - 829
  • [34] Engineering the next-generation of CAR T-cells with CRISPR-Cas9 gene editing
    Alexander Dimitri
    Friederike Herbst
    Joseph A. Fraietta
    Molecular Cancer, 21
  • [35] HEK293T Cells with TFAM Disruption by CRISPR-Cas9 as a Model for Mitochondrial Regulation
    de Oliveira, Vanessa Cristina
    Santos Roballo, Kelly Cristine
    Mariano Junior, Clesio Gomes
    Santos, Sarah Ingrid Pinto
    Bressan, Fabiana Fernandes
    Chiaratti, Marcos Roberto
    Tucker, Elena J.
    Davis, Erica E.
    Concordet, Jean-Paul
    Ambrosio, Carlos Eduardo
    LIFE-BASEL, 2022, 12 (01):
  • [36] Engineering the next-generation of CAR T-cells with CRISPR-Cas9 gene editing
    Dimitri, Alexander
    Herbst, Friederike
    Fraietta, Joseph A.
    MOLECULAR CANCER, 2022, 21 (01)
  • [37] Improving CAR T cell efficacy in pancreatic cancer using an in vivo CRISPR Cas9 screen
    Kienka, Tamina
    Korell, Felix
    Knudsen, Nelson
    Yates, Kathleen
    Cheng, Andi
    Sen, Debattama
    Maus, Marcela
    Manguso, Robert
    CANCER RESEARCH, 2024, 84 (06)
  • [38] A CRISPR-CAS9 SCREEN IDENTIFIES NOVEL EPIGENETIC REGULATORS OF T CELL EXHAUSTION
    Bommakanti, Gayathri
    Jaensch, Elizabeth
    Gorthi, Aparna
    Tan, Sin Lih
    Brucklacher-Waldert, Verena
    Criscione, Steven
    Mele, Deanna
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 10 : A1460 - A1461
  • [39] Optimized nanoparticle-mediated delivery of CRISPR-Cas9 system for B cell intervention
    Li, Min
    Fan, Ya-Nan
    Chen, Zhi-Yao
    Luo, Ying-Li
    Wang, Yu-Cai
    Lian, Zhe-Xiong
    Xu, Cong-Fei
    Wang, Jun
    NANO RESEARCH, 2018, 11 (12) : 6270 - 6282
  • [40] In Vivo delivery of CRISPR-Cas9 ribonucleoprotein complex to the retina via a cell penetrating peptide
    Yanez, Vanessa
    Kumar-Singh, Rajendra
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2019, 60 (09)