Clinical and Pathologic Features Associated with Invasive Breast Carcinoma with 2018 ASCO/CAP Group ISH 2 Results (HER2/CEP17 ratio ≥2.0 and Average HER2 Copy Number of <4.0)

被引:0
|
作者
Hoda, Raza [1 ]
McIntire, Patrick [1 ]
Komforti, Miglena [1 ]
Downs-Kelly, Erinn [1 ]
机构
[1] Cleveland Clin, Cleveland, OH 44106 USA
关键词
D O I
暂无
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
100
引用
收藏
页码:111 / 113
页数:3
相关论文
共 50 条
  • [21] Breast Cancers with HER2/CEP17 Ratio ≥2.0 and an Average HER2 Copy Number < 4.0 per Cell: Clinicopathologic Features and Alternative Chromosome 17 Probe Analysis of 102 Cases from a Single Institution Study
    Bai, Qianming
    Zhou, Shuling
    Zhu, Xiaoli
    Zhou, Xiaoyan
    Yang, Wentao
    MODERN PATHOLOGY, 2019, 32
  • [22] Breast Cancers with < 4 HER2 Signals/cell and Amplified HER2:CEP17 Ratios by FISH: Pathologic Features and Clinical Outcomes of Cases with "CEP17 Monosomy"
    Ballard, Morgan
    Troxell, Megan
    Jensen, Kristin
    Allison, Kimberly H.
    LABORATORY INVESTIGATION, 2017, 97 : 31A - 31A
  • [23] Breast Cancers with < 4 HER2 Signals/cell and Amplified HER2:CEP17 Ratios by FISH: Pathologic Features and Clinical Outcomes of Cases with "CEP17 Monosomy"
    Ballard, Morgan
    Troxell, Megan
    Jensen, Kristin
    Allison, Kimberly H.
    MODERN PATHOLOGY, 2017, 30 : 31A - 31A
  • [24] Prevalence of polysomy 17 by OncoScan in Fluorescence In Situ Hybridization (FISH) HER2 Gene amplification by HER2 gene copy number of > 6.0 with HER2/CEP17 ratio of < 2.0 in breast cancer
    Apple, Sophia
    Murata-Collins, Joyce
    MODERN PATHOLOGY, 2018, 31 : 45 - 45
  • [25] Prevalence of polysomy 17 by OncoScan in Fluorescence In Situ Hybridization (FISH) HER2 Gene amplification by HER2 gene copy number of > 6.0 with HER2/CEP17 ratio of < 2.0 in breast cancer
    Apple, Sophia
    Murata-Collins, Joyce
    LABORATORY INVESTIGATION, 2018, 98 : 45 - 45
  • [26] HER2 positive breast cancers with HER2:CEP17 ratio ≥2 and copy number >4 and <8 should require additional workup as recommended for Press groups G2-G4 in the 2018 ASCO/CAP HER2 update
    Ericsson, Paula Gonzalez
    Rexer, Brent
    Wheeler, Ferrin
    Yenamandra, Ashwini
    Sanders, Melinda
    MODERN PATHOLOGY, 2019, 32
  • [27] HER2 positive breast cancers with HER2: CEP17 ratio ≥2 and copy number > 4 and < 8 should require additional workup as recommended for Press groups G2-G4 in the 2018 ASCO/CAP HER2 update
    Ericsson, Paula Gonzalez
    Rexer, Brent
    Wheeler, Ferrin
    Yenamandra, Ashwini
    Sanders, Melinda
    LABORATORY INVESTIGATION, 2019, 99
  • [28] Retrospective observational study of HER2 immunohistochemistry in borderline breast cancer patients undergoing neoadjuvant therapy, with an emphasis on Group 2 (HER2/CEP17 ratio ≥2.0, HER2 copy number <4.0 signals/cell) cases
    Emad A. Rakha
    Islam M. Miligy
    Cecily M. Quinn
    Elena Provenzano
    Abeer M. Shaaban
    Caterina Marchiò
    Michael S. Toss
    Grace Gallagy
    Ciara Murray
    Janice Walshe
    Ayaka Katayama
    Karim Eldib
    Nahla Badr
    Bruce Tanchel
    Rebecca Millican-Slater
    Colin Purdie
    Dave Purnell
    Sarah E. Pinder
    Ian O. Ellis
    Andrew H. S. Lee
    British Journal of Cancer, 2021, 124 : 1836 - 1842
  • [29] Impact of Chromosome 17 and HER2 Copy Number Variability on HER2 FISH in Breast Cancer Cases with CEP17 Copy Number Alterations
    Donaldson, Alana R.
    Shetty, Shashirekha
    Rivera, Christine
    Portier, Bryce P.
    Cook, James R.
    Budd, G. T.
    Downs-Kelly, Erinn
    Klein, Roger D.
    Lanigan, Christopher P.
    Tubbs, Raymond
    Calhoun, Benjamin C.
    LABORATORY INVESTIGATION, 2016, 96 : 40A - 41A
  • [30] Impact of Chromosome 17 and HER2 Copy Number Variability on HER2 FISH in Breast Cancer Cases with CEP17 Copy Number Alterations
    Donaldson, Alana R.
    Shetty, Shashirekha
    Rivera, Christine
    Portier, Boyce P.
    Cook, James R.
    Budd, G. T.
    Downs-Kelly, Erinn
    Klein, Roger D.
    Lanigan, Christopher P.
    Tubbs, Raymond
    Calhoun, Benjamin C.
    MODERN PATHOLOGY, 2016, 29 : 40A - 41A