A mathematical model for the influenza virus life cycle

Motivation: The Influenza virus (Vinf) is a widespread infectious agent causing contagious disease in humans and animals. Its prominent feature is high and functional genetic variability. The mechanisms underlying virus give rise to strains possessing novel unpredictable properties. Their analysis and reliable prediction are the tasks of basic and applied biogenetics and virology. The pressing question is: What may be the replication pattern of the Vinf within the infected host cell? There is, as yet, no clarity. This is a stumbling block for advancement in this research area. Results: Here, we have reconstructed the gene network and develop a mathematical model for the Vinf. They incorporate the processes of replication, transcription, translation, regulation them and assembly within the Vinf infected cell. Based on the mathematical model, we followed the dynamics of the developed gene network and analyzed the key regulatory stages of the Vinf replication.