[1,2,4]triazolo[1,5-c]quinazolin-2(3H)-ones and their thio analogues:: a one pot synthesis

被引：0
|
作者：
Rajan, KS
Rao, ARR [1 ]
Mogilaiah, K
Prasad, MR
机构：
[1] Kakatiya Univ, Coll Pharmaceut Sci, Med Chem Div, Warangal 506009, Andhra Pradesh, India
[2] Kakatiya Univ, Dept Chem, Warangal 506009, Andhra Pradesh, India
来源：
JOURNAL OF CHEMICAL RESEARCH | 2002年 / 10期
关键词：
fused quinazolines; fused 1,2,4-triazoles; semicarbazide; thiosemicarbazide;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A facile synthetic route for 5-aryl[1,2,4]triazolo[1,5-c]quinazolin-2(3H)-ones and 2(3H)-thiones (3, 4) via 3,1-benzoxazin-4(3H)-ones in good yields under anhydrous conditions has been devised in an effort to develop new bronchodilators for the treatment of asthma.
引用
收藏
页码：490 / 492
页数：3
相关论文
共 50 条
  • [21] Alkylation of [1,2,4]triazolo[1,5-a][1,3,5]triazin-7(3H)-ones
    Irina V. Ul′yankina
    Anna V. Zavodskaya
    Victor E. Parfenov
    Alexander A. Gidaspov
    Andrey K. Shiryaev
    Eugenia V. Selezneva
    Vladimir V. Bakharev
    Chemistry of Heterocyclic Compounds, 2016, 52 : 1054 - 1060
  • [22] Alkylation of [1,2,4]triazolo[1,5-a][1,3,5]triazin-7(3H)-ones
    Ul'yankina, Irina V.
    Zavodskaya, Anna V.
    Parfenov, Victor E.
    Gidaspov, Alexander A.
    Shiryaev, Andrey K.
    Selezneva, Eugenia V.
    Bakharev, Vladimir V.
    CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2016, 52 (12) : 1054 - 1060
  • [23] One-pot synthesis of novel fused mesoionic compounds: 1-substituted-5-thioxo-5,6-dihydro-[1,2,4]triazolo[1,5-c]quinazolin-1-ium-2-thiolates
    Kovalenko, Sergiy M.
    Drushlyak, Oleksandr G.
    Mariutsa, Illia O.
    JOURNAL OF SULFUR CHEMISTRY, 2020, 41 (04) : 388 - 398
  • [24] 2-SUBSTITUTED TRIAZOLO [1,5-C] QUINAZOLIN-5(6H) ONES AND RELATED CONDENSED TRIAZOLO [1,5-C] PYRIMIDINES WITH BENZODIAZEPINE RECEPTOR-BINDING ACTIVITY
    FRANCIS, JE
    CASH, WD
    LOVELL, RA
    RINEHART, RK
    WENK, P
    WILLIAMS, M
    BENNETT, DA
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1989, 197 : 34 - MEDI
  • [25] ANXIOLYTIC PROPERTIES OF CERTAIN ANNELATED [1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5(6H)-ONES
    FRANCIS, JE
    BENNETT, DA
    HYUN, JL
    ROVINSKI, SL
    AMRICK, CL
    LOO, PS
    MURPHY, D
    NEALE, RF
    WILSON, DE
    JOURNAL OF MEDICINAL CHEMISTRY, 1991, 34 (09) : 2899 - 2906
  • [26] SYNTHESIS OF 8-NITRO-1,2,4-TRIAZOLO[1,5-C]PYRIMIDINE AND 7-METHOXY-8-NITRO-1,2,4-TRIAZOLO[1,5-C]PYRIMIDINE
    ROUSSEAUX, O
    BLONDEAU, D
    SLIWA, H
    HETEROCYCLES, 1990, 31 (02) : 277 - 281
  • [27] Effective methods of synthesis of 2-hetaryl-[1,2,4] triazolo[1,5-c] qinazolin-5(6H)-ones and their antibacterial activity
    Biliy, A. K.
    Kovalenko, S. I.
    Kamishniy, O. M.
    Polishchuk, N. M.
    ZAPOROZHYE MEDICAL JOURNAL, 2013, (06) : 83 - 87
  • [28] Synthesis and Evaluation of Novel [1,2,4]Triazolo[1,5-c]quinazoline Derivatives as Antibacterial Agents
    Zeydi, Masoud Mohammadi
    Montazeri, Naser
    Fouladi, Mahdi
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2017, 54 (06) : 3549 - 3553
  • [29] Synthesis of thiazolo[4,5-e][1,2,4]triazolo[1,5-c]pyrimidine derivatives
    Lee, Hyuck Joo
    Kim, Sung Min
    Song, Yang-Heon
    HETEROCYCLIC COMMUNICATIONS, 2013, 19 (02) : 101 - 104
  • [30] Design, Synthesis, and Photophysical Properties of 5-Aminobiphenyl Substituted [1,2,4]Triazolo[4,3-c]- and [1,2,4]Triazolo[1,5-c]quinazolines
    Moshkina, Tatyana N.
    Kopotilova, Alexandra E.
    Ivan'kina, Marya A.
    Starnovskaya, Ekaterina S.
    Gazizov, Denis A.
    Nosova, Emiliya V.
    Kopchuk, Dmitry S.
    El'tsov, Oleg S.
    Slepukhin, Pavel A.
    Charushin, Valery N.
    MOLECULES, 2024, 29 (11):
12345