Total synthesis of sphingofungin F

被引：15
|
作者：
Li, Min
Wu, Anmei
机构：
[1] Georgetown Univ, Med Ctr, Dept Neurosci, Washington, DC 20057 USA
[2] Orgchem Technol Inc, Chicago, IL 60612 USA
来源：
SYNLETT | 2006年 / 18期
关键词：
sphingofungin F; total synthesis; Michael addition; L-quebrachitol; Wittig-type reaction;
D O I：
10.1055/s-2006-947333
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A stercoselective approach toward sphingofungin F has been realized from L-quebrachitol. This synthesis featured a substrate-controlled asymmetric Michael addition, a regiospecific methylsulfonate elimination to construct the contiguous chiral centers in the target molecule.
引用
收藏
页码：2985 / 2988
页数：4
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