Antiplasmodial Activity and Cytotoxicity of Isolated Compound from the Stem Bark of Anthocleista liebrechtsiana

被引：0

作者：

Kowa, Theodora K. ^{[1
,2
]}

Zofou, Denis ^{[3
]}

Mbouangouere, Roukayatou ^{[1
]}

Tala, Michel F. ^{[1
,4
]}

Wabo, Hippolyte K. ^{[1
]}

Tan, Ning-Hua ^{[4
]}

Titanji, Vincent P. K. ^{[3
]}

Tane, Pierre ^{[1
]}

机构：

[1] Univ Dschang, Fac Sci, Dept Chem, POB 67, Dschang, Cameroon

[2] Inst Med Res & Med Plants Studies IMPM, POB 6163, Yaounde, Cameroon

[3] Univ Buea, Biotechnol Unit, POB 63, Buea, Cameroon

[4] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650204, Yunnan, Peoples R China

来源：

RECORDS OF NATURAL PRODUCTS | 2016年 / 10卷 / 03期

关键词：

Anthocleista liebrechtsiana; Loganiaceae; cerebroside; structure elucidation; antiplasmodial activity; CERAMIDE;

D O I：

暂无

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

One new cerebroside derivative, namely liebrechtsianoside A (1), along with five known compounds: tetracosanoic acid (2), swertiaperennin (3), decussatin (4), swertianin (5) and beta-sitosterol glucoside (6) were isolated from the the stem bark of Anthocleista liebrechtsiana. Their structures were elucidated by interpretation of NMR and MS data, and by comparison of these data with those reported in literature. Compound 1 showed the highest antiplasmodial activity against Dd2 chloroquine-resistant strain of Plasmodium falciparum.

引用

页码：287 / 293

页数：7

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