Individualized Homeopathic Medicines in Stage I Essential Hypertension: A Double-Blind, Randomized, Placebo-Controlled Pilot Trial

被引:2
|
作者
Sadhukhan, Satarupa [1 ]
Singh, Subhas [2 ]
Michael, James [1 ]
Misra, Pankhuri [3 ]
Parewa, Maneet [4 ]
Nath, Arunava [1 ]
Magotra, Nitin [1 ]
Kundu, Nivedita [1 ]
Basu, Anamika [5 ]
Ali, Sk Swaif [5 ]
Koley, Munmun [6 ]
Saha, Subhranil [7 ]
机构
[1] Natl Inst Homoeopathy, Dept Organon Med & Homoeopath Philosophy, Kolkata, India
[2] Natl Inst Homoeopathy, Kolkata, India
[3] Natl Inst Homoeopathy, Dept Mat Med, Kolkata, India
[4] Natl Inst Homoeopathy, Dept Repertory, Kolkata, India
[5] Mahesh Bhattacharyya Homoeopath Med Coll & Hosp, Dept Practice Med, Govt West Bengal, Howrah, India
[6] State Natl Homoeopath Med Coll & Hosp, Dept Organon Med & Homoeopath Philosophy, Govt Uttar Pradesh, Lucknow, Uttar Pradesh, India
[7] DN Homoeopath Med Coll & Hosp, Dept Repertory, Govt West Bengal, Kolkata, India
关键词
essential hypertension; homeopathy; placebo; pilot trial; randomized controlled trial; BLOOD-PRESSURE; PUBLICATION; DRUG;
D O I
10.1089/acm.2020.0222
中图分类号
R [医药、卫生];
学科分类号
10 ;
摘要
Objective: The present study assessed the feasibility of a definitive placebo-controlled trial for evaluating individualized homeopathy (IH) in stage I hypertension (HTN). Design: Double-blind, randomized (IH: 34, placebo: 34), placebo-controlled, parallel arms, pilot trial. Settings/Location: National Institute of Homoeopathy, India. Subjects: Patients suffering from stage I HTN. Interventions: IH and identical-looking placebo. Outcome measures: Feasibility issues, blood pressure (BP) and Measure Yourself Medical Outcome Profile-2 (MYMOP-2) were assessed for 6 months. Results: The recruitment and retention rates were 44.4% and 85.3%, respectively. Group differences were seemingly higher in the IH group than in the placebo group. Conclusions: Despite challenges in recruitment, an adequately powered efficacy trial appears feasible in the future.
引用
收藏
页码:515 / 521
页数:7
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