latent periodicity;
alignment;
information decomposition;
noise decomposition;
profile analysis;
repeats;
D O I:
暂无
中图分类号:
Q5 [生物化学];
学科分类号:
071010 ;
081704 ;
摘要:
Motivation: The sequences of proteins possessing strongly divergent periodicity are especially poorly studied at present. Using the developed original methods we have investigated the presence of the latent periodicity in amino acid sequences of various proteins and its connection with evolutionary formation of genes and protein functions. Results: We have revealed 100 protein families for which from 70 up to 100 % of the proteins included in them possess the same kind of the latent periodicity. The periodicity of the certain length and type is a characteristic of each family. We suppose that latent periodicity of functional domains in proteins has the common character and can be found for all known protein families.
机构:
Ragon Inst MGH & Harvard, Cambridge, MA USA
MIT, Dept Chem Engn, Cambridge, MA 02139 USA
MIT, Dept Phys, Cambridge, MA 02139 USA
MIT, Inst Med Engn & Sci, 77 Massachusetts Ave, Cambridge, MA 02139 USARagon Inst MGH & Harvard, Cambridge, MA USA
Barton, John P.
Chakraborty, Arup K.
论文数: 0引用数: 0
h-index: 0
机构:
Ragon Inst MGH & Harvard, Cambridge, MA USA
MIT, Dept Chem Engn, Cambridge, MA 02139 USA
MIT, Dept Phys, Cambridge, MA 02139 USA
MIT, Dept Chem, Cambridge, MA 02139 USA
MIT, Dept Biol Engn, 77 Massachusetts Ave, Cambridge, MA 02139 USA
MIT, Inst Med Engn & Sci, 77 Massachusetts Ave, Cambridge, MA 02139 USARagon Inst MGH & Harvard, Cambridge, MA USA
Chakraborty, Arup K.
论文数: 引用数:
h-index:
机构:
Cocco, Simona
Jacquin, Hugo
论文数: 0引用数: 0
h-index: 0
机构:
CNRS, Lab Phys Stat, ENS, UMR 8550, 24 Rue Lhomond, F-75005 Paris, France
Univ Paris 06, 24 Rue Lhomond, F-75005 Paris, FranceRagon Inst MGH & Harvard, Cambridge, MA USA
Jacquin, Hugo
Monasson, Remi
论文数: 0引用数: 0
h-index: 0
机构:
Univ Paris 06, 24 Rue Lhomond, F-75005 Paris, France
CNRS, Phys Theor Lab, ENS, UMR 8549, 24 Rue Lhomond, F-75005 Paris, FranceRagon Inst MGH & Harvard, Cambridge, MA USA