Voriconazole-resistant disseminated Paecilomyces variotii infection in a neutropenic patient with leukaemia on voriconazole prophylaxis

被引：20
|
作者：
Chamilos, Georgios [1 ]
Kontoyiannis, Dimitrios P. [1 ]
机构：
[1] Univ Texas MD Anderson Canc Ctr, Dept Infect Dis Infect Control & Employee Hlth, Unit 402,1515 Holcombe Blvd, Houston, TX 77030 USA
来源：
JOURNAL OF INFECTION | 2005年 / 51卷 / 04期
关键词：
Fungal infection; Paecilomyces; Resistance; Voriconazole;
D O I：
10.1016/j.jinf.2005.02.005
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Paecilomyces variotii, an emerging hyalohyphomycetes, has been reported to be susceptible in vitro to voriconazole. We describe a case of disseminated P. variotii infection in a neutropenic child with relapsed leukaemia who was on voriconazole prophylaxis. The P. variotii isolate was resistant to voriconazole in vitro. The patient responded to liposomal amphotericin B. (C) 2005 The British Infection Society. Published by Elsevier Ltd. All rights reserved.
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页码：E225 / E228
页数：4
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