Synthesis of 1-[4-(1,3-diaryl-4,5-dihydro-1H-pyrazol-5-yl)-2,3,5,6-tetrafluorophenyl]piperidin-4-ols and their acrylates

被引：4
|
作者：
Soboleva, E. A. [1 ]
Orlova, N. A. [1 ]
Shelkovnikov, V. V. [1 ,2 ]
机构：
[1] Russian Acad Sci, Siberian Branch, Vorozhtsov Novosibirsk Inst Organ Chem, Pr Akad Lavrenteva 9, Novosibirsk 630090, Russia
[2] Novosibirsk State Tech Univ, Pr Karla Marksa 20, Novosibirsk 630073, Russia
来源：
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2017年 / 53卷 / 03期
基金：
俄罗斯基础研究基金会;
关键词：
PYRAZOLINE DERIVATIVES; FLUORESCENCE; CHALCONES;
D O I：
10.1134/S1070428017030149
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
(4-Hydroxypiperidin-1-yl)tetra- and -octafluorochalcones reacted with phenylhydrazine in acetic acid to give mixtures of polyfluoro-1,3,5-triaryl-4,5-dihydro-1H-pyrazoles and their O-acetyl derivatives. Analogous reactions in ethanol afforded in satisfactory yields 1-[4-(1,3-diaryl-4,5-dihydro-1H-pyrazol-5-yl)-2,3,5,6-tetrafluorophenyl]piperidin-4-ols which were treated with acryloyl chloride to obtain the corresponding acrylates that are promising as monomers for the preparation of fluorescent films.
引用
收藏
页码：398 / 406
页数：9
相关论文
共 50 条
  • [21] 4-[3,4-Dimethyl-1-(4-methylphenyl)-5oxo-4,5-dihydro-1H-pyrazol-4-yl]-3,4dimethyl-1-(4-methylphenyl)-4,5dihydro-1H-pyrazol-5-one
    Wardell, Solange M. S. V.
    Howie, Alan H.
    Tiekink, Edward R. T.
    Wardell, James L.
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2012, 68 : O992 - +
  • [22] Synthesis of 4,5-dihydro-1H-pyrazol-5-yl-substituted 1,2,3-triazoles
    A. A. Golovanov
    I. S. Odin
    Russian Journal of Organic Chemistry, 2015, 51 : 447 - 448
  • [23] Synthesis of 4,5-dihydro-1H-pyrazol-5-yl-substituted 1,2,3-triazoles
    Golovanov, A. A.
    Odin, I. S.
    RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2015, 51 (03) : 447 - 448
  • [24] 1-[5-(4-Chlorophenyl)-3-(4-hydroxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]-ethanone
    Fun, Hoong-Kun
    Quah, Ching Kheng
    Priya, S.
    Narayana, B.
    Sarojini, B. K.
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2012, 68 : O818 - U2817
  • [25] 1-[3-(4-Chlorophenyl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl]-ethanone
    Fun, Hoong-Kun
    Quah, Ching Kheng
    Samshuddin, S.
    Narayana, B.
    Sarojini, B. K.
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2012, 68 : O1023 - +
  • [26] 1-[5-(4-Methoxyphenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl]ethanone
    Abbas, Asghar
    Hussain, Safdar
    Hafeez, Noureen
    Lo, Kong Mun
    Hasan, Aurangzeb
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 : O3174 - U680
  • [27] 1-[5-(4-Bromophenyl)-3-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl]-ethanone
    Fun, Hoong-Kun
    Loh, Wan-Sin
    Sapnakumari, M.
    Narayana, B.
    Sarojini, B. K.
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2012, 68 : 02586 - +
  • [28] 1-[3-(4-methoxyphenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl]ethanone
    Jian, Fang-Fang
    Wang, Jing
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2006, 62 : O5303 - O5304
  • [29] 1-[3-(4-Fluorophenyl)-5-phenyl-4,5dihydro-1H-pyrazol-1-yl]ethanone
    Fun, Hoong-Kun
    Ooi, Chin Wei
    Sapnakumari, M.
    Narayana, B.
    Sarojini, B. K.
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2012, 68 : O2634 - +
  • [30] A simplified synthesis of 2,3,5,6-tetrafluorophenyl 2-(2-nitroimidazol-1-yl) acetate
    Wilson, H
    JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 2003, 46 (06): : 511 - 513
12345