Markovnikov-Selective Hydroboration of Olefins Catalyzed by a Copper N-Heterocyclic Carbene Complex

被引：12
|
作者：
DiBenedetto, Tarah A. [1 ]
Parsons, Astrid M. [1 ]
Jones, William D. [1 ]
机构：
[1] Univ Rochester, Dept Chem, Rochester, NY 14627 USA
来源：
ORGANOMETALLICS | 2019年 / 38卷 / 17期
关键词：
ENANTIOSELECTIVE HYDROBORATION; ASYMMETRIC HYDROBORATION; REACTIVITY;
D O I：
10.1021/acs.organomet.9b00394
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
The efficient and atom-economical hydroboration of alkenes and alkynes using an N-heterocyclic carbene (NHC) copper hydroxide catalyst has been developed. An equimolar combination of substrate and HBpin allows for the selective Markovnikov hydroboration of alkenes and alkynes. A variety of functional groups were tolerated in good to excellent yield. This system features a facile reaction setup, atom economy, high selectivity, and an easily synthesized copper-NHC catalyst.
引用
收藏
页码：3322 / 3326
页数：5
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