Although there is controversy regarding the benefit of early detection of prostate cancer, it has been demonstrated that early detection can be best achieved through the use of a combination of digital rectal examination and prostate-specific antigen (PSA). This article outlines the clinical use of PSA for early detection of prostate cancer and focuses primarily on the value of molecular forms of PSA (free PSA, complexed PSA, and total PSA) in the diagnosis of localized prostate cancer.
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Med Univ Graz, Dept Pathol, Graz, Austria
Cornell Univ, Weill Cornell Med Coll, New York, NY 10021 USAUniv Clin Eppendorf, Dept Urol, Hamburg, Germany
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Nanjing Med Univ, Dept Lab Med, Affiliated Hosp 1, Nanjing, Jiangsu, Peoples R China
Oriental & Foreign Related Hosp, Dept Lab Med, Lianyungang, Peoples R ChinaNanjing Med Univ, Dept Lab Med, Affiliated Hosp 1, Nanjing, Jiangsu, Peoples R China
Huang, Hui-Qing
Zhang, Yan
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Nanjing Med Univ, Dept Lab Med, Affiliated Hosp 1, Nanjing, Jiangsu, Peoples R ChinaNanjing Med Univ, Dept Lab Med, Affiliated Hosp 1, Nanjing, Jiangsu, Peoples R China
Zhang, Yan
Xu, Hua-Guo
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Nanjing Med Univ, Dept Lab Med, Affiliated Hosp 1, Nanjing, Jiangsu, Peoples R ChinaNanjing Med Univ, Dept Lab Med, Affiliated Hosp 1, Nanjing, Jiangsu, Peoples R China