The use of prostate-specific antigen and free/total prostate-specific antigen in the diagnosis of localized prostate cancer

被引:32
|
作者
Partin, AW [1 ]
Carter, HB [1 ]
机构
[1] JOHNS HOPKINS MED INST, BRADY UROL INST, DEPT UROL, BALTIMORE, MD 21205 USA
关键词
D O I
10.1016/S0094-0143(05)70333-5
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Although there is controversy regarding the benefit of early detection of prostate cancer, it has been demonstrated that early detection can be best achieved through the use of a combination of digital rectal examination and prostate-specific antigen (PSA). This article outlines the clinical use of PSA for early detection of prostate cancer and focuses primarily on the value of molecular forms of PSA (free PSA, complexed PSA, and total PSA) in the diagnosis of localized prostate cancer.
引用
收藏
页码:531 / +
页数:1
相关论文
共 50 条
  • [31] A comparative performance analysis of total prostate-specific antigen, percentage free prostate-specific antigen, prostate-specific antigen velocity and urinary prostate cancer gene 3 in the first, second and third repeat prostate biopsy
    Auprich, Marco
    Augustin, Herbert
    Budaeus, Lars
    Kluth, Luis
    Mannweiler, Sebastian
    Shariat, Shahrokh F.
    Fisch, Margit
    Graefen, Markus
    Pummer, Karl
    Chun, Felix K. -H.
    [J]. BJU INTERNATIONAL, 2012, 109 (11) : 1627 - 1635
  • [32] THE USE OF PROSTATE-SPECIFIC ANTIGEN DENSITY TO IMPROVE THE SENSITIVITY OF PROSTATE-SPECIFIC ANTIGEN IN DETECTING PROSTATE CARCINOMA
    BRETTON, PR
    EVANS, WP
    BORDEN, JD
    CASTELLANOS, RD
    [J]. CANCER, 1994, 74 (11) : 2991 - 2995
  • [33] Comparison of three assays for total serum prostate-specific antigen and percentage of free prostate-specific antigen in predicting prostate histology
    Roehrborn, CG
    Gregory, A
    Mcconnell, JD
    Sagalowsky, AI
    Wians, FH
    [J]. UROLOGY, 1996, 48 (6A) : 23 - 32
  • [34] CANCER (PROSTATE-SPECIFIC ANTIGEN)
    CASTELLANI, WJ
    [J]. ANALYTICAL CHEMISTRY, 1995, 67 (12) : R399 - R403
  • [35] Different free prostate-specific antigen to total prostate-specific antigen ratios using three detecting systems
    Huang, Hui-Qing
    Zhang, Yan
    Xu, Hua-Guo
    [J]. JOURNAL OF CLINICAL LABORATORY ANALYSIS, 2018, 32 (02)
  • [36] Using the free-to-total prostate-specific antigen ratio to detect prostate cancer in men with nonspecific elevations of prostate-specific antigen levels
    Richard M. Hoffman
    David L. Clanon
    Benjamin Littenberg
    Joseph J. Frank
    John C. Peirce
    [J]. Journal of General Internal Medicine, 2000, 15 : 739 - 748
  • [37] Using the free-to-total prostate-specific antigen ratio to detect prostate cancer in men with nonspecific elevations of prostate-specific antigen levels
    Hoffman, RM
    Clanon, DL
    Littenberg, B
    Frank, JJ
    Peirce, JC
    [J]. JOURNAL OF GENERAL INTERNAL MEDICINE, 2000, 15 (10) : 739 - 748
  • [38] Prostate-specific antigen velocity and repeated measures of prostate-specific antigen
    Carter, HB
    Pearson, JD
    [J]. UROLOGIC CLINICS OF NORTH AMERICA, 1997, 24 (02) : 333 - &
  • [39] Urinary/serum prostate-specific antigen ratio:: Comparison with free/total serum prostate-specific antigen ratio in improving prostate cancer detection
    Irani, J
    Salomon, L
    Soulié, M
    Zlotta, A
    de la Taille, A
    Doré, B
    Millet, C
    [J]. UROLOGY, 2005, 65 (03) : 533 - 537
  • [40] Prostate-specific antigen adjusted for the transition zone volume versus free-to-total prostate-specific antigen ratio in predicting prostate cancer
    Moon, DG
    Cheon, J
    Kim, JJ
    Yoon, DK
    Koh, SK
    [J]. INTERNATIONAL JOURNAL OF UROLOGY, 1999, 6 (09) : 455 - 462