The anti-Candida activity of Shikon

被引：25
|
作者：
Sasaki, K
Yoshizaki, F
Abe, H
机构：
[1] Tohoku Pharmaceut Univ, Aoba Ku, Sendai, Miyagi 9818558, Japan
[2] Senseki Hosp, Monou, Miyagi 9810501, Japan
来源：
YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN | 2000年 / 120卷 / 06期
关键词：
acetylshikonin; Candida albicans; Lithospermum erythrorhizon; Arnebia euchroma;
D O I：
10.1248/yakushi1947.120.6_587
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Antifungal activity of Shikon, roots of Lithospermum erythrorhizon and Arnebia euchroma was investigated in vitro. The extracts containing the pigments of Ko-shikon or Nan-shikon showed the antifungal activities against Candida albicans. Acetylshikonin, one of these pigments, inhibited the fungal growth at MIC 15.6 mu g/ml (RPMI24h) or 3.9 mu g/ml (YNB24 h).
引用
收藏
页码：587 / 589
页数：3
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