Development of rheumatoid arthritis following autologous peripheral blood stem cell transplantation

被引：17
|
作者：
Imamura, R [1 ]
Inoue, H [1 ]
Kato, K [1 ]
Kobayashi, S [1 ]
Tsukamoto, H [1 ]
Nagafuji, K [1 ]
Shimoda, K [1 ]
Nakashima, H [1 ]
Otsuka, T [1 ]
Gondo, H [1 ]
Harada, M [1 ]
机构：
[1] Kyushu Univ, Grad Sch Med Sci, Higashi Ku, Fukuoka 8128582, Japan
来源：
BONE MARROW TRANSPLANTATION | 2002年 / 30卷 / 08期
关键词：
autologous stem cell transplantation; peripheral blood stem cell transplantation; rheumatoid arthritis;
D O I：
10.1038/sj.bmt.1703664
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
A 51-year-old man with non-Hodgkin's lymphoma (NHL) was treated with high-dose chemotherapy followed by autologous peripheral blood stem cell transplantation (PBSCT). Although he had HLA-DRB1 0405 and a positive rheumatoid factor, he was unlikely to develop rheumatoid arthritis (RA) according to diagnostic criteria. However, the patient developed RA 40 days after transplantation. Our experience suggests that the systemic autoimmune disease, RA, may occur in patients with predisposing factors after autologous PBSCT.
引用
收藏
页码：527 / 529
页数：3
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