Substituted bicyclic 2-pyridones inhibits the cytotoxic effect of Aα42 oligomers

被引：0
|
作者：
Vestling, M.
Nimmervoll, B.
Aberg, V.
Chorell, E.
Lundgren, E.
Sauer-Eriksson, E.
Olofsson, A.
Almqvist, F.
机构：
[1] Dept Mol Biol, Umea, Sweden
[2] Dept Chem, Umea, Sweden
[3] Umea Univ, Umea Ctr Mol Pathogenesis, Umea, Sweden
来源：
AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS | 2006年 / 13卷
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：66 / 66
页数：1
相关论文
共 50 条
  • [41] STRUCTURE AND CATALYTIC ACTIVITY OF SUBSTITUTED 2-PYRIDONES IN AMINOLYSIS REACTION OF BENZOIC-ACID HALIDES
    SAVELOVA, VA
    LITVINENKO, LM
    SKRIPKA, AV
    ZHURNAL ORGANICHESKOI KHIMII, 1980, 16 (01): : 110 - 119
  • [42] Selective CB2 agonists with anti-pruritic activity: Discovery of potent and orally available bicyclic 2-pyridones
    Kusakabe, Ken-ichi
    Iso, Yasuyoshi
    Tada, Yukio
    Sakagami, Masahiro
    Morioka, Yasuhide
    Chomei, Nobuo
    Shinonome, Satomi
    Kawamoto, Keiko
    Takenaka, Hideyuki
    Yasui, Kiyoshi
    Hamana, Hiroshi
    Hanasaki, Kohji
    BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 21 (11) : 3154 - 3163
  • [43] DIMER FORMATION ENERGIES OF MONOMETHYL-SUBSTITUTED 2-PYRIDONES AND THEIR ULTRAVIOLET-ABSORPTION SPECTRA
    FUJIMOTO, A
    INUZUKA, K
    SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 1985, 41 (12): : 1471 - 1475
  • [44] NEW METHOD FOR SYNTHESIS OF BICYCLIC AND TRICYCLIC 2-PYRIDONES FROM 1-AMINO-2-CYANO-1-CYCLOPENTENE AND KETONES
    UPADYSHEVA, AV
    GRIGOREVA, ND
    SERGEEVA, GS
    ZNAMENSKAYA, AP
    ZHURNAL ORGANICHESKOI KHIMII, 1976, 12 (03): : 687 - 687
  • [45] DIELS-ALDER CYCLOADDITIONS USING NUCLEOPHILIC 2-PYRIDONES - REGIOCONTROLLED AND STEREOCONTROLLED SYNTHESIS OF UNSATURATED, BRIDGED, BICYCLIC LACTAMS
    POSNER, GH
    VINADER, V
    AFARINKIA, K
    JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (15): : 4088 - 4097
  • [46] Modulation of α-synuclein fibrillization by ring-fused 2-pyridones: Templation and inhibition involve oligomers with different structure
    Horvath, Istvan
    Sellstedt, Magnus
    Weise, Christoph
    Nordvall, Lina-Maria
    Prasad, G. Krishna
    Olofsson, Anders
    Larsson, Goran
    Almqvist, Fredrik
    Wittung-Stafshede, Pernilla
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2013, 532 (02) : 84 - 90
  • [47] Facile, one-pot synthesis of bicyclic 2-pyridones from acyl isocyanates, N-phenylmaleimide and trimethylsilyldiazomethane
    Hari, Y
    Iguchi, T
    Aoyama, T
    SYNTHESIS-STUTTGART, 2005, (13): : 2147 - 2150
  • [48] A novel strategy for alkylation via amide activation: synthesis of N-substituted 2-pyridones and tetrahydropyridines
    Song, Qiao
    Wang, Shun
    Wang, Sheng
    Xing, Dong
    Wang, Zhouyu
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2025,
  • [49] A comparison of N- versus O-alkylation of substituted 2-pyridones under Mitsunobu conditions
    Torhan, Matthew C.
    Peet, Norton P.
    Williams, John D.
    TETRAHEDRON LETTERS, 2013, 54 (30) : 3926 - 3928
  • [50] SPECIFIC-INHIBITION OF HUMAN-LEUKOCYTE ELASTASE BY SUBSTITUTED ALPHA-PYRONES AND 2-PYRIDONES
    GROUTAS, WC
    ABRAMS, WR
    CARROLL, RT
    MOI, MK
    MILLER, KE
    MARGOLIS, MT
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1983, 186 (AUG): : 96 - MEDI
12345