Evaluation of commercially available recombinant human P450s and anti-human P450 antibodies

被引:0
|
作者
Madden, S [1 ]
Paton, J [1 ]
Phillips, M [1 ]
Cameron, B [1 ]
机构
[1] Inveresk Res Int Ltd, Tranent EH33 2NE, E Lothian, Scotland
关键词
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
59
引用
收藏
页码:30 / 30
页数:1
相关论文
共 50 条
  • [21] Inhibition of human recombinant cytochrome P450s by curcumin and curcumin decomposition products
    Appiah-Opong, Regina
    Commandeur, Jan N. M.
    van Vugt-Lussenburg, Barbara
    Vermeulen, Nico P. E.
    TOXICOLOGY, 2007, 235 (1-2) : 83 - 91
  • [22] Human hepatocytes and cytochrome P450-selective inhibitors predict variability in human drug exposure more accurately than human recombinant P450s
    Lindmark, Bo
    Lundahl, Anna
    Kanebratt, Kajsa P.
    Andersson, Tommy B.
    Isin, Emre M.
    BRITISH JOURNAL OF PHARMACOLOGY, 2018, 175 (11) : 2116 - 2129
  • [23] Specificity of substrate and inhibitor probes for cytochrome P450s: Evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes
    Ono, S
    Hatanaka, T
    Hotta, H
    Satoh, T
    Gonzalez, FJ
    Tsutsui, M
    XENOBIOTICA, 1996, 26 (07) : 681 - 693
  • [24] Biotransformation of chlorpyrifos and diazinon by human liver microsomes and recombinant human cytochrome P450s (CYP)
    Sams, C
    Cocker, J
    Lennard, MS
    XENOBIOTICA, 2004, 34 (10) : 861 - 873
  • [25] The cytochrome P450 genesis locus: the origin and evolution of animal cytochrome P450s
    Nelson, David R.
    Goldstone, Jared V.
    Stegeman, John J.
    PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2013, 368 (1612)
  • [26] Metabolism of palmatine by human hepatocytes and recombinant cytochromes P450
    Vrba, Jiri
    Papouskova, Barbora
    Pyszkova, Michaela
    Zatloukalova, Martina
    Lemr, Karel
    Ulrichova, Jitka
    Vacek, Jan
    JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2015, 102 : 193 - 198
  • [27] Bioactivation of tamoxifen by recombinant human cytochrome P450 enzymes
    Notley, LM
    de Wolf, CJF
    Wunsch, RM
    Lancaster, RG
    Gillam, EMJ
    CHEMICAL RESEARCH IN TOXICOLOGY, 2002, 15 (05) : 614 - 622
  • [28] In vitro stability of human recombinant cytochrome P450 enzymes
    Yang, Jiansong
    Tucker, Geoffrey T.
    Rostami-Hodjegan, Amin
    DRUG METABOLISM REVIEWS, 2006, 38 : 102 - 102
  • [29] Improved cloning and expression of cytochrome P450s and cytochrome P450 reductase in yeast
    Hamann, Thomas
    Moller, Birger Lindberg
    PROTEIN EXPRESSION AND PURIFICATION, 2007, 56 (01) : 121 - 127
  • [30] Metabolism of Echinacea alkamides by human recombinant P450 enzymes
    Toselli, F.
    Matthias, A.
    Bone, K. M.
    Gillam, E. M. J.
    Lehmann, R. P.
    PLANTA MEDICA, 2008, 74 (09) : 921 - 921