Inherited cancer syndromes in gynaecology:: what the practitioner needs to know!

被引：0

作者：

Kuschel, B

Köchli, OR

Niederacher, D

Müller, H

Beckmann, MW

机构：

[1] Univ Dusseldorf, Frauenklin, D-4000 Dusseldorf, Germany

[2] Univ Basel, Kantonsspital, Frauenklin, CH-4031 Basel, Switzerland

[3] UKBB, Abt Med Genet, Basel, Switzerland

来源：

SCHWEIZERISCHE MEDIZINISCHE WOCHENSCHRIFT | 2000年 / 130卷 / 10期

关键词：

inherited cancer syndromes; genetic testing; gynaecological oncology;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

During the last 5 years progress in molecular genetics has offered the possibility of genetic testing for inherited mutations of cancer-predisposing genes. The exact cellular function and carcinogenic potential of these genes is yet not completely understood. Only in 5-20% of all cancers inherited genetic mutations play an important role in the polygenic and multifactorial nature of the disease. Identification of inherited cancer syndromes, predictive genetic testing, and counselling of women and family members at increased risk is of clinical importance. The debate surrounding presymptomatic diagnostic testing and adequate programmes for early cancer detection, prevention or clinical follow-up continues.

引用

页码：362 / 375

页数：16

共 50 条

[1] Manual of Cancer Treatment Recovery: What the Practitioner Needs to Know and Do
Key, R. Garrett
[J]. PSYCHO-ONCOLOGY, 2013, 22 (01) : 239 - 239
[2] The "envirome" and what the practitioner needs to know about it
Peden, David B.
[J]. ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, 2019, 123 (06) : 542 - 549
[3] THE FELINE LIVER - WHAT A PRACTITIONER NEEDS TO KNOW
HITT, ME
JONES, BD
CONSTANTINESCU, G
[J]. VETERINARY MEDICINE, 1987, 82 (02) : 129 - &
[4] DIALYSIS AT HOME, WHAT A PRACTITIONER NEEDS TO KNOW
TRAEGER, J
[J]. LYON MEDICAL, 1978, 239 (07): : 425 - 428
[5] Transcultural considerations in obstetrics and gynaecology: What the clinician needs to know
Kotsapas, C.
Dixon, C.
Nauta, M.
Fakokunde, A.
Yoong, W.
[J]. JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 2009, 29 (03) : 175 - 180
[6] Cancer: What the Primary Care Practitioner Needs to Know, Part II - Foreword
Heidelbaugh, Joel J.
[J]. PRIMARY CARE, 2009, 36 (04): : XIII - XIV
[7] The reconstructive oral cancer patient: what the general dental practitioner needs to know
Araghi, Ariyan S.
Nasry, Hany
[J]. BRITISH DENTAL JOURNAL, 2019, 227 (08) : 689 - 692
[8] Cancer: What the Primary Care Practitioner Needs to Know, Part I Foreword
Heidelbaugh, Joel J.
[J]. PRIMARY CARE, 2009, 36 (03): : XIII - XV
[9] Cancer: What the Primary Care Practitioner Needs to Know, Part I Preface
Wender, Richard
Snyderman, Danielle
[J]. PRIMARY CARE, 2009, 36 (03): : XVII - XVIII
[10] The reconstructive oral cancer patient: what the general dental practitioner needs to know
Ariyan S. Araghi
Hany Nasry
[J]. British Dental Journal, 2019, 227 : 689 - 692

← 1 2 3 4 5 →