Sertraline in the treatment of major depression following mild traumatic brain injury

被引：131
|
作者：
Fann, JR
Uomoto, JM
Katon, WJ
机构：
[1] Univ Washington, Dept Psychiat & Behav Sci, Seattle, WA 98195 USA
[2] Seattle Pacific Univ, Dept Grad Psychol, Seattle, WA 98119 USA
来源：
JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES | 2000年 / 12卷 / 02期
关键词：
D O I：
10.1176/appi.neuropsych.12.2.226
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
An 8-week, nonrandomized, single-blind, placebo run-in trial Of sertraline was conducted on 15 patients diagnosed with major depression between 3 and 24 months after a mild traumatic brain injury. On the Hamilton Rating Scale for Depression, 13 (87%) han a decrease in score of greater than or equal to 50% ("response"), and 10 (67%) achieved ct score of less than or equal to 7 ("remission") by week 8 of sertraline. There was statistically significant improvement in psychological distress, anger and aggression, functioning, ann postconcussive symptoms with treatment.
引用
收藏
页码：226 / 232
页数：7
相关论文
共 50 条
  • [21] Investigating Depression Following Mild Head Injury and Moderate Traumatic Brain Injury: Is it Different?
    Robb, Sean
    Good, Dawn
    [J]. JOURNAL OF HEAD TRAUMA REHABILITATION, 2015, 30 (03) : E93 - E94
  • [22] The serotonin transporter polymorphisms and major depression following traumatic brain injury
    Chan, Florance
    Lanctot, Krista L.
    Feinstein, Anthony
    Herrmann, Nathan
    Strauss, John
    Sicard, Tricia
    Kennedy, James L.
    McCullagh, Scott
    Rapoport, Mark J.
    [J]. BRAIN INJURY, 2008, 22 (06) : 471 - 479
  • [23] Role of Sertraline in Post Traumatic brain injury (TBI) Depression and Quality of Life in Traumatic Brain Injury
    Jain, Akhilesh
    Ansari, Ahmed
    Sharma, Achal
    Mittal, R. S.
    Gupta, I. D.
    [J]. INDIAN JOURNAL OF PSYCHIATRY, 2015, 57 (05) : S18 - S18
  • [24] Current treatment options for depression after mild traumatic brain injury
    Esther Bay
    [J]. Current Treatment Options in Neurology, 2009, 11
  • [25] Current treatment options for depression after mild traumatic brain injury
    Bay, Esther
    [J]. CURRENT TREATMENT OPTIONS IN NEUROLOGY, 2009, 11 (05) : 377 - 382
  • [26] Depression following traumatic brain injury
    Rosenthal, M
    Christensen, BK
    Ross, TP
    [J]. ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION, 1998, 79 (01): : 90 - 103
  • [27] Effect Of Anxiety And Depression On Athlete Return To Play Following Mild Traumatic Brain Injury
    Kebort, Breanna M.
    Kampert, Matthew
    Spindler, Kurt
    Figler, Richard
    Farokhrani, Amin
    [J]. MEDICINE & SCIENCE IN SPORTS & EXERCISE, 2022, 54 (09) : 327 - 327
  • [28] Risk Factors for Developing Novel Depression and Anxiety Following Mild Traumatic Brain Injury
    Ballatori, Alexander
    Haddad, Alison
    Shahrestani, Shane
    [J]. JOURNAL OF HEAD TRAUMA REHABILITATION, 2022, 37 (06) : E528 - E528
  • [29] Depression Strongly Influences Postconcussion Symptom Reporting Following Mild Traumatic Brain Injury
    Lange, Rael T.
    Iverson, Grant L.
    Rose, Alice
    [J]. JOURNAL OF HEAD TRAUMA REHABILITATION, 2011, 26 (02) : 127 - 137
  • [30] INCIDENCE OF DEPRESSION FOLLOWING TRAUMATIC BRAIN INJURY
    Albrecht, J.
    Barbour, L.
    Abariga, S.
    Rao, V
    Perfetto, E. M.
    [J]. VALUE IN HEALTH, 2018, 21 : S182 - S182
12345