High Throughput Morphology-Based Cell Screening by Reservoir Computing
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作者:
Jing, Ning
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Univ Kent, Sch Engn & Digital Arts, Canterbury, Kent, England
North Univ China Taiyuan, Sch Informat & Commun Engn, Taiyuan, Peoples R ChinaUniv Kent, Sch Engn & Digital Arts, Canterbury, Kent, England
Jing, Ning
[1
,2
]
Wang, Chao
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Univ Kent, Sch Engn & Digital Arts, Canterbury, Kent, EnglandUniv Kent, Sch Engn & Digital Arts, Canterbury, Kent, England
Wang, Chao
[1
]
机构:
[1] Univ Kent, Sch Engn & Digital Arts, Canterbury, Kent, England
[2] North Univ China Taiyuan, Sch Informat & Commun Engn, Taiyuan, Peoples R China
A new low-cost and data-efficient method for high-throughput microfluidic single-cell screening is proposed and demonstrated. Only one low-speed single-pixel photodetector is needed. Morphology-based object classification is achieved using reservoir computing. Our experiment shows that the frames involving the target cell can be recognized distinctly.
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US EPA, Off Res & Dev, Great Lakes Toxicol & Ecol Div, 6201 Congdon Blvd, Duluth, MN 55804 USAUS EPA, Off Res & Dev, Great Lakes Toxicol & Ecol Div, 6201 Congdon Blvd, Duluth, MN 55804 USA
Hoffman, Joel Christopher
Meredith, Christy
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Montana Dept Environm Qual, 1520 E 6th Ave, Helena, MT 59601 USAUS EPA, Off Res & Dev, Great Lakes Toxicol & Ecol Div, 6201 Congdon Blvd, Duluth, MN 55804 USA
Meredith, Christy
Pilgrim, Erik
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US EPA, Off Res & Dev, Watershed & Ecosyst Characterizat Div, 26 West Martin Luther King Dr, Cincinnati, OH 45268 USAUS EPA, Off Res & Dev, Great Lakes Toxicol & Ecol Div, 6201 Congdon Blvd, Duluth, MN 55804 USA
Pilgrim, Erik
Trebitz, Anett
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US EPA, Off Res & Dev, Great Lakes Toxicol & Ecol Div, 6201 Congdon Blvd, Duluth, MN 55804 USAUS EPA, Off Res & Dev, Great Lakes Toxicol & Ecol Div, 6201 Congdon Blvd, Duluth, MN 55804 USA
Trebitz, Anett
Hatzenbuhler, Chelsea
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US EPA, Badger Tech Serv, Off Res & Dev, Great Lakes Toxicol & Ecol Div, 6201 Congdon Blvd, Duluth, MN 55804 USAUS EPA, Off Res & Dev, Great Lakes Toxicol & Ecol Div, 6201 Congdon Blvd, Duluth, MN 55804 USA
Hatzenbuhler, Chelsea
Kelly, John Russell
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US EPA, Off Res & Dev, Great Lakes Toxicol & Ecol Div, 6201 Congdon Blvd, Duluth, MN 55804 USAUS EPA, Off Res & Dev, Great Lakes Toxicol & Ecol Div, 6201 Congdon Blvd, Duluth, MN 55804 USA
Kelly, John Russell
Peterson, Gregory
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US EPA, Off Res & Dev, Great Lakes Toxicol & Ecol Div, 6201 Congdon Blvd, Duluth, MN 55804 USAUS EPA, Off Res & Dev, Great Lakes Toxicol & Ecol Div, 6201 Congdon Blvd, Duluth, MN 55804 USA
Peterson, Gregory
Lietz, Julie
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US EPA, Off Res & Dev, Great Lakes Toxicol & Ecol Div, 6201 Congdon Blvd, Duluth, MN 55804 USAUS EPA, Off Res & Dev, Great Lakes Toxicol & Ecol Div, 6201 Congdon Blvd, Duluth, MN 55804 USA
Lietz, Julie
Okum, Sara
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US EPA, Off Res & Dev, Watershed & Ecosyst Characterizat Div, 26 West Martin Luther King Dr, Cincinnati, OH 45268 USAUS EPA, Off Res & Dev, Great Lakes Toxicol & Ecol Div, 6201 Congdon Blvd, Duluth, MN 55804 USA
Okum, Sara
Martinson, John
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US EPA, Off Res & Dev, Great Lakes Toxicol & Ecol Div, 26 West Martin Luther King Dr, Cincinnati, OH 45268 USAUS EPA, Off Res & Dev, Great Lakes Toxicol & Ecol Div, 6201 Congdon Blvd, Duluth, MN 55804 USA
机构:Cheeloo College of Medicine,Key Laboratory of Chemical Biology of Natural Products (Ministry of Education), Institute of Biochemical and Biotechnological Drug, School of Pharmaceutical Sciences
Zi-Xu Liu
Si-Ling Huang
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机构:Cheeloo College of Medicine,Key Laboratory of Chemical Biology of Natural Products (Ministry of Education), Institute of Biochemical and Biotechnological Drug, School of Pharmaceutical Sciences
Si-Ling Huang
Jin Hou
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机构:Cheeloo College of Medicine,Key Laboratory of Chemical Biology of Natural Products (Ministry of Education), Institute of Biochemical and Biotechnological Drug, School of Pharmaceutical Sciences
Jin Hou
Xue-Ping Guo
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机构:Cheeloo College of Medicine,Key Laboratory of Chemical Biology of Natural Products (Ministry of Education), Institute of Biochemical and Biotechnological Drug, School of Pharmaceutical Sciences
Xue-Ping Guo
Feng-Shan Wang
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机构:Cheeloo College of Medicine,Key Laboratory of Chemical Biology of Natural Products (Ministry of Education), Institute of Biochemical and Biotechnological Drug, School of Pharmaceutical Sciences
Feng-Shan Wang
Ju-Zheng Sheng
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机构:Cheeloo College of Medicine,Key Laboratory of Chemical Biology of Natural Products (Ministry of Education), Institute of Biochemical and Biotechnological Drug, School of Pharmaceutical Sciences
机构:
Chinese Acad Sci, Shanghai Inst Mat Med, Natl Ctr Drug Screening, Shanghai 201203, Peoples R China
Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R ChinaChinese Acad Sci, Shanghai Inst Mat Med, Natl Ctr Drug Screening, Shanghai 201203, Peoples R China
Zhang, Zhiyun
Guan, Ni
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Chinese Acad Sci, Shanghai Inst Mat Med, Natl Ctr Drug Screening, Shanghai 201203, Peoples R China
Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R ChinaChinese Acad Sci, Shanghai Inst Mat Med, Natl Ctr Drug Screening, Shanghai 201203, Peoples R China
Guan, Ni
Li, Ting
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Chinese Acad Sci, Shanghai Inst Mat Med, Natl Ctr Drug Screening, Shanghai 201203, Peoples R China
Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R ChinaChinese Acad Sci, Shanghai Inst Mat Med, Natl Ctr Drug Screening, Shanghai 201203, Peoples R China
Li, Ting
Mais, Dale E.
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MPI Res, Mattawan, MI 49071 USAChinese Acad Sci, Shanghai Inst Mat Med, Natl Ctr Drug Screening, Shanghai 201203, Peoples R China
Mais, Dale E.
Wang, Mingwei
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Chinese Acad Sci, Shanghai Inst Mat Med, Natl Ctr Drug Screening, Shanghai 201203, Peoples R China
Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R ChinaChinese Acad Sci, Shanghai Inst Mat Med, Natl Ctr Drug Screening, Shanghai 201203, Peoples R China
机构:
Harvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Dept Med, Boston, MA 02215 USAHarvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Dept Med, Boston, MA 02215 USA
Radomska, Hanna S.
Jernigan, Finith
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Harvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Dept Surg, Boston, MA 02215 USAHarvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Dept Med, Boston, MA 02215 USA
Jernigan, Finith
Nakayama, Sohei
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Harvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Dept Med, Boston, MA 02215 USAHarvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Dept Med, Boston, MA 02215 USA
Nakayama, Sohei
Jorge, Susan E.
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Harvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Dept Med, Boston, MA 02215 USAHarvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Dept Med, Boston, MA 02215 USA
Jorge, Susan E.
Sun, Lijun
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Harvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Dept Surg, Boston, MA 02215 USAHarvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Dept Med, Boston, MA 02215 USA
Sun, Lijun
Tenen, Daniel G.
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Harvard Univ, Sch Med, Harvard Stem Cell Inst, Boston, MA 02115 USA
Natl Univ Singapore, Canc Sci Inst, Singapore 117548, SingaporeHarvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Dept Med, Boston, MA 02215 USA
Tenen, Daniel G.
Kobayashi, Susumu S.
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Harvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Dept Med, Boston, MA 02215 USA
Harvard Univ, Sch Med, Harvard Stem Cell Inst, Boston, MA 02115 USAHarvard Univ, Beth Israel Deaconess Med Ctr, Sch Med, Dept Med, Boston, MA 02215 USA