Moderate hypothermia technique for chronic implantation of a total artificial heart in calves

被引：0

作者：

Karimov, Jamshid H. ^{[1
]}

Grady, Patrick ^{[2
]}

Sinkewich, Martin ^{[2
]}

Sunagawa, Gengo ^{[1
]}

Dessoffy, Raymond ^{[1
]}

Byram, Nicole ^{[1
]}

Moazami, Nader ^{[1
,3
]}

Fukamachi, Kiyotaka ^{[1
]}

机构：

[1] Cleveland Clin, Lerner Res Inst, Dept Biomed Engn ND20, 9500 Euclid Ave, Cleveland, OH 44195 USA

[2] Cleveland Clin, Perfus Serv, Cardiac Surg, Cleveland, OH 44106 USA

[3] Cleveland Clin, Dept Thorac & Cardiovasc Surg, Kaufman Ctr Heart Failure, Inst Heart & Vasc, Cleveland, OH 44106 USA

来源：

JOURNAL OF ARTIFICIAL ORGANS | 2017年 / 20卷 / 02期

基金：

美国国家卫生研究院;

关键词：

Assisted circulation; Heart-assist devices; Hypothermia; Experimental surgery;

D O I：

10.1007/s10047-017-0946-9

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

The benefit of whole-body hypothermia in preventing ischemic injury during cardiac surgical operations is well documented. However, application of hypothermia during in vivo total artificial heart implantation has not become widespread because of limited understanding of the proper techniques and restrictions implied by constitutional and physiological characteristics specific to each animal model. Similarly, the literature on hypothermic set-up in total artificial heart implantation has also been limited. Herein we present our experience using hypothermia in bovine models implanted with the Cleveland Clinic continuous-flow total artificial heart.

引用

页码：182 / 185

页数：4

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