Amorphane sesquiterpenes from a marine Streptomyces sp.

被引：46
|
作者：
Wu, Shao Jie
Fotso, Serge
Li, Fuchao
Qin, Song
Laatsch, Hartmut
机构：
[1] Univ Gottingen, Dept Organ & Biomol Chem, D-37077 Gottingen, Germany
[2] Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China
[3] Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
来源：
JOURNAL OF NATURAL PRODUCTS | 2007年 / 70卷 / 02期
关键词：
D O I：
10.1021/np050358e
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
The chemical investigation of the crude extract of the marine-derived Streptomyces sp. M491 yielded three new sesquiterpenes, namely, 10 alpha,11-dihydroxyamorph-4-ene (4), 10 alpha,15-dihydroxyamorph-4-en-3-one (6), and 5 alpha,10 alpha,11-trihydroxyamorphan-3-one (7). In addition, the known compounds 10 alpha-hydroxyamorph-4-en-3-one (2), o-hydroxyacetanilide, genistein, prunetin, and indole-3-carbaldehyde and the macrolide antibiotic chalcomycin A were identified. The structures were determined on the basis of spectroscopic analysis, especially 1D and 2D NMR data. This is the first report of these sesquiterpenes from bacteria.
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收藏
页码：304 / 306
页数：3
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