A new isobenzofuranone derivative from a marine Streptomyces sp.

被引：13
|
作者：
Xie, Ze Ping [2 ,4 ]
Zhang, Hong Yu [2 ,4 ]
Li, Fu Chao [1 ]
Liu, Bing [2 ]
Yang, Sheng Xiang [3 ]
Wang, Hong Peng [5 ]
Pu, Yang [2 ,4 ]
Chen, Yi [6 ]
Qin, Song [2 ]
机构：
[1] Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China
[2] Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
[3] NW A&F Univ, Coll Sci, Chem Biol Res Inst, Yangling 712100, Peoples R China
[4] Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
[5] Univ Gottingen, Dept Organ & Biomol Chem, D-37077 Gottingen, Germany
[6] Zhejiang Med Co Ltd, Xinchang Pharmaceut Factory, Xinchang 312500, Peoples R China
来源：
CHINESE CHEMICAL LETTERS | 2012年 / 23卷 / 08期
基金：
中国国家自然科学基金;
关键词：
Isobenzofuranone; Marine Streptomyces; Bioactivity; PESTALOTIOPSIS-MICROSPORA; ANTIOXIDANT;
D O I：
10.1016/j.cclet.2012.06.001
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
One new isobenzofuranone derivative, 1,4-dimethoxy-3-(3R*-hydroxy-3R*-methyl-1-tetralone)-1(3H)-isobenzofuran (1), was isolated from the broth of marine Streptomyces sp. M268. The structure was elucidated by spectroscopy characteristics as well as comparison with the literature. Compound 1 exhibited cytotoxicities against human cancer cell, HL-60, A549, and BEL-7402. (C) 2012 Fu Chao Li. Published by Elsevier B.V, on behalf of Chinese Chemical Society. All rights reserved.
引用
收藏
页码：941 / 944
页数：4
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