An Implantable Wireless Optogenetic Stimulation System for Peripheral Nerve Control

被引：0

作者：

Song, Kang-Il ^{[1
,2
]}

Park, Sunghee E. ^{[1
]}

Kim, Myoung-Soo ^{[2
]}

Joo, Chulmin ^{[2
]}

Kim, Yong-Jun ^{[2
]}

Suh, Jun-Kyo F. ^{[1
]}

Hwang, Dosik ^{[2
]}

Youn, Inchan ^{[1
]}

机构：

[1] Korea Inst Sci & Technol, Seoul 136791, South Korea

[2] Yonsei Univ, Seoul 120749, South Korea

来源：

2015 37TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC) | 2015年

关键词：

D O I：

暂无

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

An implantable wireless optogenetic stimulation system with an LED-based optical stimulation cuff electrode was developed for peripheral nerve control. The proposed system consisted of a battery-powered optical cuff electrode, optical stimulation controller, and wireless communication system. The optical cuff electrode had a polydimethylsiloxane (PDMS) structure was designed to illuminate the entire sciatic nerve. The wireless communication system was designed to comply with medical implant communication service (MICS) regulations. To evaluate the proposed system, optogenetic stimulation was performed in optogenetic transgenic mice (Thy1::ChR2). The optical cuff electrode was implanted on the sciatic nerve, and movement was elicited during optical stimulation. The experimental results show that ankle movement can be generated wirelessly using optical stimulation pulse parameters.

引用

页码：1033 / 1036

页数：4

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