Pharmacologic Therapy of Non-Alcoholic Steatohepatitis

被引：24

作者：

Ratziu, Vlad ^{[1
]}

Zelber-Sagi, Shira ^{[2
,3
]}

机构：

[1] Univ Paris 06, APHP, Hop Pitie Salpetriere, F-75013 Paris, France

[2] Tel Aviv Sourasky Med Ctr, Dept Gastroenterol, Liver Unit, IL-64239 Tel Aviv, Israel

[3] Univ Haifa, Sch Publ Hlth, IL-31999 Haifa, Israel

来源：

CLINICS IN LIVER DISEASE | 2009年 / 13卷 / 04期

关键词：

Non-alcoholic steatohepatitis; Steatosis; Fibrosis; Glitazones; Ursodesoxycholic acid; Sartans; Orlistat; Hepatoprotectants; FATTY LIVER-DISEASE; PLACEBO-CONTROLLED TRIAL; STELLATE CELL ACTIVATION; NECROSIS-FACTOR-ALPHA; RENIN-ANGIOTENSIN SYSTEM; II RECEPTOR ANTAGONIST; LOW-CARBOHYDRATE-DIET; WEIGHT-LOSS DIETS; INSULIN-RESISTANCE; VITAMIN-E;

D O I：

10.1016/j.cld.2009.07.001

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Specific therapy for non-alcoholic steatohepatitis (NASH) is needed because of the potential severity of this liver disease. NASH is a recognized cause of cryptogenic cirrhosis and, increasingly, of hepatocellular carcinoma. Therefore, there is an unmet medical need for the therapy of NASH. This article discusses this therapy, with particular emphasis on pharmacologic therapy.

引用

页码：667 / +

页数：23

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