Knoevenagel condensation reaction catalysed by agro-waste extract as a greener solvent catalyst

被引:23
|
作者
Badiger, Krishnappa B. [1 ]
Kamanna, Kantharaju [1 ]
机构
[1] Rani Channamma Univ, Dept Chem, Peptide & Med Chem Res Lab, P-B,NH-4, Belagavi 591156, India
关键词
one-pot reaction; green chemistry; solvent-free; Knoevenagel condensation reaction; malononitrile; room temperature; ACTIVE METHYLENE-COMPOUNDS; AROMATIC-ALDEHYDES; WATER EXTRACT; HETEROGENEOUS CATALYST; EFFICIENT; LIQUID; MALONONITRILE; PHASE; ACID;
D O I
10.25135/acg.oc.99.21.01.1948
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
This paper present a novel Knoevenagel reaction protocol for the condensation of aromatic/heteroaromatic aldehydes with malononitrile to give alpha, beta-unsaturated benzylidene derivatives. The main focus of this work is to reveal the usability of agro-waste extracts as a catalyst in the Knoevenagel condensation. The present protocol proceeds efficiently for various substituted aromatic and heterocyclic aldehydes in the Knoevenagel reactions. In addition, the present method describes direct isolation of the formed products without using organic solvent extraction gave good yields product. (C) 2021 ACG Publication. All right reserved.
引用
收藏
页码:81 / 91
页数:11
相关论文
共 50 条
  • [31] Fluorapatite: new solid catalyst of the Knoevenagel reaction in heterogeneous media without solvent
    Sebti, S
    Nazih, R
    Tahir, R
    Salhi, L
    Saber, H
    APPLIED CATALYSIS A-GENERAL, 2000, 197 (02) : L187 - L190
  • [32] Microwave enhanced solvent-free, rapid and efficient Knoevenagel condensation using KF as catalyst
    Mogilaiah, K
    Rani, JU
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2003, 13 (02) : 169 - 170
  • [33] A Facile, Efficient and Solvent-Free Titanium (IV) Ethoxide Catalysed Knoevenagel Condensation of Aldehydes and Active Methylenes
    Ramaiah, Manjunatha M.
    Shivananju, Nanjunda Swamy
    Shubha, Priya Babu
    LETTERS IN ORGANIC CHEMISTRY, 2020, 17 (02) : 107 - 115
  • [34] Ca-Containing Mesoporous Silica as a Solid Base Catalyst for the Knoevenagel Condensation Reaction
    Keita Ikeue
    Nao Miyoshi
    Takayuki Tanaka
    Masato Machida
    Catalysis Letters, 2011, 141
  • [35] A New Mixed-Metal Phosphate as an Efficient Heterogeneous Catalyst for Knoevenagel Condensation Reaction
    Chowdhury, Avik
    Bhattacharjee, Sudip
    Chongdar, Sayantan
    Malakar, Bhabani
    Maity, Anindita
    Bhaumik, Asim
    CATALYSTS, 2023, 13 (07)
  • [36] Amine functionalized MCM-41: An active and reusable catalyst for Knoevenagel condensation reaction
    Parida, K. M.
    Rath, Dharitri
    JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL, 2009, 310 (1-2) : 93 - 100
  • [37] Synthesis and characterization of amine functionalized graphene oxide and scope as catalyst for Knoevenagel condensation reaction
    Rana, Surjyakanta
    Jonnalagadda, Sreekantha B.
    CATALYSIS COMMUNICATIONS, 2017, 92 : 31 - 34
  • [38] Ca-Containing Mesoporous Silica as a Solid Base Catalyst for the Knoevenagel Condensation Reaction
    Ikeue, Keita
    Miyoshi, Nao
    Tanaka, Takayuki
    Machida, Masato
    CATALYSIS LETTERS, 2011, 141 (06) : 877 - 881
  • [39] Facile functionalization of graphene oxide with ethylenediamine as a solid base catalyst for Knoevenagel condensation reaction
    Xue, Bing
    Zhu, Jiagui
    Liu, Na
    Li, Yongxin
    CATALYSIS COMMUNICATIONS, 2015, 64 : 105 - 109
  • [40] Enhanced reaction rate by using N,N-dimethylformamide as a catalyst in Knoevenagel condensation
    Jain, Swareena
    Maidh, Tavleen
    Badole, Madhavi
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2020, 59 (07): : 1025 - 1029