Cost analysis of migraine pharmacotherapy with selective 5HT1 receptor agonists in Ukraine

被引:0
|
作者
Hrynkiv, Yaryna [1 ]
Zaliska, Olha [1 ]
Maksymovych, Nataliia [1 ]
Blavatska, Oksana [1 ]
机构
[1] Danylo Halytsky Lviv Natl Med Univ, Lvov, Ukraine
关键词
selective 5HT1-receptor agonists; zolmitriptan; rizatriptan; sumatriptan; frovatriptan; cost of pharmacotherapy; migraine attack; RIZATRIPTAN;
D O I
10.3897/pharmacia.68.e51740
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The cost analysis for the relief of migraine attack using selective 5HT1-receptor agonists (frovatriptan, zolmitriptan, risatriptan, sumatriptan) of domestic and imported manufacturers in various dosages and forms of production in the proposed resource online pharmacy chains of Lviv for their efficient and cost effective applications. Among the registered drugs, most dosage forms and trade names are presented for sumatriptan; slightly less for risatriptan and zolmitriptan; for frovatriptan is only one trade name. It has been found that to relieve migraine attack with domestic drugs will be cheaper for patients than imported. Packaging with the same dosage of active ingredient, but with more tablets in the blister is more cost effective for patients. It`s the most economical to stop the migraine attack with Stopmigren (sumatriptan) at a dosage of 50 mg, packing 6 tablets in a blister, and the most valuable drug is Rapimig (zolmitriptan) at a dosage of 50 mg, packing 6 tablets in a blister.
引用
收藏
页码:235 / 241
页数:7
相关论文
共 50 条
  • [31] RATIONALE FOR THE USE OF 5-HT1-LIKE AGONISTS IN THE TREATMENT OF MIGRAINE
    FENIUK, W
    HUMPHREY, PPA
    PERREN, MJ
    CONNOR, HE
    WHALLEY, ET
    JOURNAL OF NEUROLOGY, 1991, 238 : S57 - S61
  • [32] Human 5-HT1D-receptor agonists
    Lloyd, AW
    DRUG DISCOVERY TODAY, 2000, 5 (01) : 33 - 33
  • [33] A BEHAVIORAL AND BIOCHEMICAL-STUDY IN MICE AND RATS OF PUTATIVE SELECTIVE AGONISTS AND ANTAGONISTS FOR 5-HT1-RECEPTOR AND 5-HT2-RECEPTOR
    GOODWIN, GM
    GREEN, AR
    BRITISH JOURNAL OF PHARMACOLOGY, 1985, 84 (03) : 743 - 753
  • [34] Selective, orally active 5-HT1D receptor agonists as potential antimigraine agents
    MacLeod, AM
    Street, LJ
    Reeve, AJ
    Jelley, RA
    Sternfeld, F
    Beer, MS
    Stanton, JA
    Watt, AP
    Rathbone, D
    Matassa, VG
    JOURNAL OF MEDICINAL CHEMISTRY, 1997, 40 (22) : 3501 - 3503
  • [35] Effects of highly or relatively selective 5-HT1A receptor agonists on lordosis in female rats
    Kishitake, M
    Yamanouchi, K
    ZOOLOGICAL SCIENCE, 2003, 20 (09) : 1133 - 1138
  • [36] 5-Thienyltryptamine derivatives as serotonin 5-HT1B/1D receptor agonists:: Potential treatments for migraine
    Meng, CQ
    Rakhit, S
    Lee, DKH
    Kambo, R
    McCallum, KL
    Mazzocco, L
    Dyne, K
    Slassi, A
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2000, 10 (09) : 903 - 905
  • [37] Influence of a 5HT1 receptor agonist on gastric accommodation and initial transpyloric flow in healthy subjects
    Vingerhagen, S
    Hausken, T
    Gilja, OH
    Berstad, A
    NEUROGASTROENTEROLOGY AND MOTILITY, 2000, 12 (01): : 95 - 101
  • [38] Analysis of the haemodynamic effects of 5-HT1B/D receptor agonists in the rat
    Pagniez, F
    Valentin, JP
    Vieu, S
    John, GW
    BRITISH JOURNAL OF PHARMACOLOGY, 1997, 122 : U44 - U44
  • [39] Clarifications on the effects of 5-HT1A agonists and selective 5-HT reuptake inhibitors on the 5-HT system
    Blier, P
    deMontigny, C
    NEUROPSYCHOPHARMACOLOGY, 1996, 15 (02) : 213 - 214
  • [40] Serotonin 5-HT1B/1D receptor agonists in migraine -: Comparative pharmacology and its therapeutic implications
    Goadsby, PJ
    CNS DRUGS, 1998, 10 (04) : 271 - 286