Age at menopause predicts age at onset of Parkinson's disease

被引：43
|
作者：
Ragonese, Paolo
D'Amelio, Marco
Callari, Graziella
Salemi, Giuseppe
Morgante, Letterio
Savettieri, Giovanni
机构：
[1] Univ Palermo, Dipartimento Neurosci Clin, Palermo, Italy
[2] Univ Messina, Dept Neurol, I-98100 Messina, Italy
来源：
MOVEMENT DISORDERS | 2006年 / 21卷 / 12期
关键词：
Parkinson's disease; age at menopause; women; fertile life; risk factors;
D O I：
10.1002/mds.21127
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
We investigated the association between age at onset of Parkinson's disease (PD) and fertile life characteristics in 145 women. Linear regression analyses showed a significant correlation between age at PD onset and age at menopause (P = 0.003), between age at PD onset and fertile life duration (P = 0.008), and a nonsignificant correlation between PD onset and cumulative duration of pregnancies (P = 0.23). These results support the possible role of estrogens in PD. (C) 2006 Movement Disorder Society.
引用
收藏
页码：2211 / 2214
页数：4
相关论文
共 50 条
  • [31] Does age at onset of Parkinson's disease affect the development of dementia?
    Soliveri, P.
    Del Sorbo, F.
    Zecchinelli, A.
    Sacilotto, G.
    Meucci, N.
    Zini, M.
    Mariani, C.
    Tesei, S.
    Pezzoli, G.
    [J]. MOVEMENT DISORDERS, 2020, 35 : S186 - S186
  • [32] Serotonergic Degeneration in Parkinson's Disease: What Is the Link With the Age of Onset?
    Macerollo, Antonella
    [J]. CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES, 2020, 47 (03) : 287 - 288
  • [33] Levodopa-dyskinesia incidence by age of Parkinson's disease onset
    Kumar, N
    Van Gerpen, JA
    Bower, JH
    Ahlskog, JE
    [J]. MOVEMENT DISORDERS, 2005, 20 (03) : 342 - 344
  • [34] Modulation of the age at onset of Parkinson's disease by apolipoprotein E genotypes
    Zareparsi, S
    Kaye, J
    Camicioli, R
    Grimslid, H
    Oken, B
    Litt, M
    Nutt, J
    Bird, T
    Schellenberg, G
    Payami, H
    [J]. ANNALS OF NEUROLOGY, 1997, 42 (04) : 655 - 658
  • [35] GBA haplotypes and age at onset of Parkinson's disease in the Asian population
    Li, C.
    Ou, R.
    Hou, Y.
    Wei, Q.
    Zhang, L.
    Liu, K.
    Lin, J.
    Chen, X.
    Song, W.
    Zhao, B.
    Wu, Y.
    Shang, H.
    [J]. MOVEMENT DISORDERS, 2023, 38 : S482 - S482
  • [36] SNCA: Major genetic modifier of age at onset of Parkinson's disease
    Brockmann, Kathrin
    Schulte, Claudia
    Hauser, Ann-Kathrin
    Lichtner, Peter
    Huber, Heiko
    Maetzler, Walter
    Berg, Daniela
    Gasser, Thomas
    [J]. MOVEMENT DISORDERS, 2013, 28 (09) : 1217 - 1221
  • [37] Plasma Fasting Cholesterol Profiles and Age at Onset in Parkinson's Disease
    Mahlknecht, Philipp
    Sprenger, Fabienne
    Seppi, Klaus
    Poewe, Werner
    [J]. MOVEMENT DISORDERS, 2015, 30 (14) : 1974 - 1975
  • [38] Cerebral cortical thinning in Parkinson's disease depends on the age of onset
    Seo, Kazuhide
    Matunari, Ichiro
    Yamamoto, Toshimasa
    [J]. PLOS ONE, 2023, 18 (02):
  • [39] Epigenetic Clock Acceleration Is Linked to Age at Onset of Parkinson's Disease
    Tang, Xuelin
    Gonzalez-Latapi, Paulina
    Marras, Connie
    Visanji, Naomi P.
    Yang, Wanli
    Sato, Christine
    Lang, Anthony E.
    Rogaeva, Ekaterina
    Zhang, Ming
    [J]. MOVEMENT DISORDERS, 2022, 37 (09) : 1831 - 1840
  • [40] Genetic influences of MAPT and SNCA on age at onset of Parkinson's disease
    Huang, Y.
    Wang, G.
    Rowe, D.
    Wang, Y.
    Kwok, J.
    Xiao, Q.
    Masterglia, F.
    Liu, J.
    Halliday, G.
    Chen, S.
    [J]. MOVEMENT DISORDERS, 2013, 28 : S279 - S280
12345