Age at menopause predicts age at onset of Parkinson's disease

被引：43
|
作者：
Ragonese, Paolo
D'Amelio, Marco
Callari, Graziella
Salemi, Giuseppe
Morgante, Letterio
Savettieri, Giovanni
机构：
[1] Univ Palermo, Dipartimento Neurosci Clin, Palermo, Italy
[2] Univ Messina, Dept Neurol, I-98100 Messina, Italy
来源：
MOVEMENT DISORDERS | 2006年 / 21卷 / 12期
关键词：
Parkinson's disease; age at menopause; women; fertile life; risk factors;
D O I：
10.1002/mds.21127
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
We investigated the association between age at onset of Parkinson's disease (PD) and fertile life characteristics in 145 women. Linear regression analyses showed a significant correlation between age at PD onset and age at menopause (P = 0.003), between age at PD onset and fertile life duration (P = 0.008), and a nonsignificant correlation between PD onset and cumulative duration of pregnancies (P = 0.23). These results support the possible role of estrogens in PD. (C) 2006 Movement Disorder Society.
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收藏
页码：2211 / 2214
页数：4
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