Failure of mycophenolate mofetil therapy in primary refractory nephrotic syndrome

被引：0

作者：

Baglio, Veronica ^{[1
]}

Pecci, Gabriella ^{[1
]}

Gangemi, Concetta ^{[1
]}

Barresi, Giusi ^{[1
]}

Morabito, Santo ^{[1
]}

Pierucci, Alessandro ^{[1
]}

机构：

[1] Univ Roma La Sapienza, Dipartimento Sci Clin, Azienda Policlin Umberto 1, Div Nephrol, I-00161 Rome, Italy

来源：

JOURNAL OF NEPHROLOGY | 2006年 / 19卷 / 06期

关键词：

nephrotic syndrome; idiopathic membranous nephropathy; minimal change disease; myrophenolate mofetil; steroid-resistance;

D O I：

暂无

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Mycophenolate mofetil (MMF) has been suggested as a promising therapeutic agent in the treatment of idiopathic nephrotic syndrome. Two patients with persistent nephrotic syndrome, secondary to minimal change disease and idiopathic membranous nephropathy, respectively, who were steroid-, cyclophosphamide- and cyclosporine-resistant, were treated with MMF during a 6-12-month period. In these cases there was no beneficial effect from treatment with MMF. Therapy was stopped after 6 months in case I and after 12 months in case 2 due to the persistence of proteinuria.

引用

页码：819 / 824

页数：6

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