Failure of mycophenolate mofetil therapy in primary refractory nephrotic syndrome

被引:0
|
作者
Baglio, Veronica [1 ]
Pecci, Gabriella [1 ]
Gangemi, Concetta [1 ]
Barresi, Giusi [1 ]
Morabito, Santo [1 ]
Pierucci, Alessandro [1 ]
机构
[1] Univ Roma La Sapienza, Dipartimento Sci Clin, Azienda Policlin Umberto 1, Div Nephrol, I-00161 Rome, Italy
关键词
nephrotic syndrome; idiopathic membranous nephropathy; minimal change disease; myrophenolate mofetil; steroid-resistance;
D O I
暂无
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Mycophenolate mofetil (MMF) has been suggested as a promising therapeutic agent in the treatment of idiopathic nephrotic syndrome. Two patients with persistent nephrotic syndrome, secondary to minimal change disease and idiopathic membranous nephropathy, respectively, who were steroid-, cyclophosphamide- and cyclosporine-resistant, were treated with MMF during a 6-12-month period. In these cases there was no beneficial effect from treatment with MMF. Therapy was stopped after 6 months in case I and after 12 months in case 2 due to the persistence of proteinuria.
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收藏
页码:819 / 824
页数:6
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