Gold-Catalyzed Tandem Cycloisomerization-Halogenation of Chiral Homopropargyl Sulfonamides

被引：21
|
作者：
Shu, Chao [1 ,2 ]
Li, Long [1 ,2 ]
Shen, Cang-Hai [1 ,2 ]
Ruan, Peng-Peng [1 ,2 ]
Liu, Chao-Yue [1 ,2 ]
Ye, Long-Wu [1 ,2 ,3 ]
机构：
[1] Xiamen Univ, Coll Chem & Chem Engn, State Key Lab Phys Chem Solid Surfaces, Xiamen 361005, Fujian, Peoples R China
[2] Xiamen Univ, Coll Chem & Chem Engn, Key Lab Chem Biol Fujian Prov, Xiamen 361005, Fujian, Peoples R China
[3] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China
来源：
CHEMISTRY-A EUROPEAN JOURNAL | 2016年 / 22卷 / 07期
基金：
中国国家自然科学基金;
关键词：
cycloisomerization; gold; halogenation; heterocycles; homogeneous catalysis; EFFICIENT SYNTHESIS; INTERMOLECULAR OXIDATION; REGIOSELECTIVE SYNTHESIS; TERT-BUTANESULFINAMIDE; ASYMMETRIC-SYNTHESIS; ORGANOGOLD COMPOUNDS; PRACTICAL SYNTHESIS; PROPARGYLIC AMIDES; ALKYNES; DERIVATIVES;
D O I：
10.1002/chem.201503891
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Two new gold-catalyzed tandem cycloisomerization-halogenation reactions of chiral homopropargyl sulfonamides have been developed. Various enantioenriched 3,3-diiodopyrrolidin-2-ols and 3-fluoropyrrolidin-2-ols were obtained in moderate-to-good yields with excellent enantio- and diastereoselectivity.
引用
收藏
页码：2282 / 2290
页数：9
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