Why gamblers fail to win: A review of cognitive and neuroimaging findings in pathological gambling

被引：243

作者：

van Holst, Ruth J. ^{[1
]}

van den Brink, Wim ^{[1
]}

Veltman, Dick J. ^{[1
]}

Goudriaan, Anna E. ^{[1
]}

机构：

[1] Univ Amsterdam, Acad Med Ctr, Dept Psychiat, Amsterdam Inst Addict Res, NL-1105 AZ Amsterdam, Netherlands

来源：

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS | 2010年 / 34卷 / 01期

关键词：

Pathological gambling; Addiction; Cognition; Reward; Punishment; Impulsivity; Cue reactivity; Attentional bias; Decision making; fMRI; Neuroimaging; Neuropsychology; SUBSTANCE-USE DISORDERS; METHAMPHETAMINE-DEPENDENT SUBJECTS; SOMATIC MARKER HYPOTHESIS; DOPAMINE D2 RECEPTORS; CARD SORTING TEST; DECISION-MAKING; PREFRONTAL CORTEX; FRONTAL-LOBE; ANTERIOR CINGULATE; WORKING-MEMORY;

D O I：

10.1016/j.neubiorev.2009.07.007

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

The purpose of this review is to gain more insight in the neuropathology of pathological gambling (PG) and problem gambling, and to discuss challenges in this research area. Results from the reviewed PG studies show that PG is more than just an impulse control disorder. PG seems to fit very well with recent theoretical models of addiction, which stress the involvement of the ventral tegmental-orbito frontal cortex. Differentiating types of PG on game preferences (slot machines vs. casino games) seems to be useful because different PG groups show divergent results, suggesting different neurobiological pathways to PG. A framework for future studies is suggested, indicating the need for hypothesis driven pharmacological and functional imaging studies in PG and integration of knowledge from different research areas to further elucidate the neurobiological underpinnings of this disorder. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：87 / 107

页数：21