Potential role of PM2.5 in melanogenesis

被引：26

作者：

Peng, Fen ^{[1
]}

Tsuji, Gaku ^{[2
,3
]}

Zhang, Jian-zhong ^{[1
]}

Chen, Zhou ^{[1
]}

Furue, Masutaka ^{[2
,3
,4
]}

机构：

[1] Peking Univ, Peoples Hosp, Dept Dermatol, Beijing 100044, Peoples R China

[2] Kyushu Univ, Fac Med Sci, Grad Sch Med, Dept Dermatol, Fukuoka, Fukuoka 8128582, Japan

[3] Kyushu Univ Hosp, Res & Clin Ctr Yusho & Dioxin, Fukuoka, Fukuoka 8128582, Japan

[4] Kyushu Univ, Fac Med Sci, Grad Sch Med, Div Skin Surface Sensing,Dept Dermatol, Fukuoka, Fukuoka 8128582, Japan

来源：

ENVIRONMENT INTERNATIONAL | 2019年 / 132卷

关键词：

Particulate matter 2.5; Aryl hydrocarbon receptor; Reactive oxygen species; Melanogenesis; Hyperpigmentation; ARYL-HYDROCARBON RECEPTOR; POLYCYCLIC AROMATIC-HYDROCARBONS; AIRBORNE PARTICULATE MATTER; OXIDATIVE STRESS; EXPOSURE; POLLUTION; URBAN; KERATINOCYTES; MODULATION; EXPRESSION;

D O I：

10.1016/j.envint.2019.105063

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Ambient particulate matter 2.5 (PM2.5) is one of the main components of air pollutants, which can absorb many polycyclic aromatic hydrocarbons and metals. The effect of PM2.5 on human skin and its biological significance in skin homeostasis remain incompletely understood. Previous studies demonstrated that PM2.5 can activate aryl hydrocarbon receptor (AhR), generate reactive oxygen species, and induce skin inflammation. These processes may be involved in melanocyte homeostasis and melanogenesis. We hypothesize that AhR signaling may be responsible for PM2.5-related hyperpigmentation.

引用

页数：4

共 50 条

[1] Ambient PM2.5 and Health: Does PM2.5 Oxidative Potential Play a Role?
Sarnat, Stefanie Ebelt
Chang, Howard H.
Weber, Rodney J.
[J]. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2016, 194 (05) : 530 - 531
[2] PM2.5还是PM2.5
邓春琴
[J]. 编辑学报, 2014, 26 (03) : 240 - 240
[3] Oxidative potential of subway PM2.5
Moreno, Teresa
Kelly, Frank J.
Dunster, Chrissi
Oliete, Ana
Martins, Vania
Reche, Cristina
Cruz Minguillon, Maria
Amato, Fulvio
Capdevila, Marta
de Miguel, Eladio
Querol, Xavier
[J]. ATMOSPHERIC ENVIRONMENT, 2017, 148 : 230 - 238
[4] On the role of ammonia in the formation of PM2.5
Mensink, C.
Deutsch, F.
[J]. AIR POLLUTION MODELING AND ITS APPLICATION XIX, 2008, : 548 - +
[5] PM2.5
[J]. 吉林环境, 2012, (01) : 42 - 42
[6] PM2.5
刘长柏
[J]. 数学教学通讯, 2012, (11) : 10 - 11
[7] PM2.5
[J]. 中国科技产业, 2012, (04) : 24 - 24
[8] 《PM2.5》
李林
[J]. 明日风尚, 2018, (06) : 13 - 13
[9] PM2.5
[J]. 人口与计划生育, 2012, (04) : 61 - 61
[10] PM2.5
[J]. 标准生活, 2013, (12) : 64 - 65

← 1 2 3 4 5 →