Double-clad hollow core photonic crystal fiber for coherent Raman endoscope

被引:54
|
作者
Brustlein, Sophie [1 ,2 ,3 ]
Berto, Pascal [1 ,2 ,3 ]
Hostein, Richard [1 ,2 ,3 ]
Ferrand, Patrick [1 ,2 ,3 ]
Billaudeau, Cyrille [4 ,5 ,6 ]
Marguet, Didier [4 ,5 ,6 ]
Muir, Alistair [7 ]
Knight, Jonathan [7 ]
Rigneault, Herve [1 ,2 ,3 ]
机构
[1] Aix Marseille Univ, Inst Fresnel, F-13013 Marseille, France
[2] Ecole Cent Marseille, Inst Fresnel, F-13013 Marseille, France
[3] CNRS, Inst Fresnel, F-13013 Marseille, France
[4] Ctr Immunol Marseille Luminy, INSERM, UMR S 631, F-13009 Marseille, France
[5] CNRS, UMR 6102, F-13009 Marseille, France
[6] Univ Mediterranee, UM 631, F-13009 Marseille, France
[7] Univ Bath, Ctr Photon & Photon Mat, Dept Phys, Bath BA2 7AY, Avon, England
来源
OPTICS EXPRESS | 2011年 / 19卷 / 13期
关键词
GUIDANCE; LIGHT;
D O I
10.1364/OE.19.012562
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
Performing label free coherent anti-Stokes Raman scattering (CARS) and stimulated Raman scattering (SRS) in endoscope imaging is a challenge, with huge potential clinical benefit. To date, this goal has remained inaccessible because of the inherent coherent Raman noise that is generated in the fiber itself. By developing double-clad hollow core photonic crystal fiber, we demonstrate coherent anti-Stokes Raman scattering and stimulated Raman scattering in an, endoscope-like. scheme. Both the excitation beams and the collected CARS and SRS signals travel through the same fiber. No CARS and SRS signals are generated within the hollow core fiber even for temporally overlapping pump and Stokes beams, leading to excellent image quality. The CARS and SRS signals generated in the sample are coupled back into a high numerical aperture multimode cladding surrounding the central photonic crystal cladding. We demonstrate this scheme by imaging molecular vibrational bonds of organic crystal deposited on a glass surface. (C)2011 Optical Society of America
引用
收藏
页码:12562 / 12568
页数:7
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