PREPARATION OF PYRIDINE DERIVATIVES FROM THE CORRESPONDING 5-ACETAL-1-CARBONYL COMPOUNDS BY ACID PROMOTED CYCLIZATION

被引：0

作者：

Mihara, Hiromichi ^{[1
]}

Watanabe, Yuki ^{[1
]}

Konno, Hiroyuki ^{[1
]}

机构：

[1] Yamagata Univ, Dept Biol Engn, Grad Sch Sci & Engn, Yonezawa, Yamagata 9928510, Japan

来源：

HETEROCYCLES | 2021年 / 102卷 / 07期

基金：

日本学术振兴会;

关键词：

HIGHLY SUBSTITUTED PYRIDINES; CATALYZED CYCLIZATION; LIGANDS; OXIMES; ROUTE;

D O I：

10.3987/COM-21-14457

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of four alkylpyridine derivatives from 5-acetal-1-carbonyl compounds via the one-pot, acid-promoted cyclization of oxime intermediates is described. In addition, a dihydroxypyridine and pyridinium salt were also synthesized. The pyridine formation step was not affected by the stereochemistry of the precursors used.

引用

页码：1314 / 1329

页数：16

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