Pharmacokinetics of ketoprofen in the donkey (Equus asinus)

被引：12
|
作者：
Oukessou, M
Bouljihad, M
VanGool, F
Alvinerie, M
机构：
[1] Inst. Agronom. Veterinaire Hassan II, Rabat
[2] Inst. Agronom. Veterinaire Hassan II, Rabat
[3] Rhône Mérieux, Lyon
[4] Station de Pharmacologie-Toxicologie, INRA, Toulouse
来源：
JOURNAL OF VETERINARY MEDICINE SERIES A-ZENTRALBLATT FUR VETERINARMEDIZIN REIHE A-PHYSIOLOGY PATHOLOGY CLINICAL MEDICINE | 1996年 / 43卷 / 07期
关键词：
D O I：
10.1111/j.1439-0442.1996.tb00470.x
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
The pharmacokinetic parameters of ketoprofen were determined in four donkeys after a single intravenous injection of a dose of 2.2 mg/kg body weight. The total body clearance (Cl-B) was 414.0 +/- 98.70 ml/h/kg (mean +/- SD), the volume of distribution at steady state (V-5S) 263.10 +/- 55.43 ml/kg and the elimination half-life 1.30 +/- 0.75 h. These values were compared to those obtained in horses.
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页码：423 / 426
页数：4
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