Screening test data analysis for liver disease prediction model using growth curve

被引:20
|
作者
Kim, YS
Sohn, SY
Yoon, CN
机构
[1] Korea Inst Sci & Technol, Bioanal Biotransform & Res Ctr, Seoul 130650, South Korea
[2] Yonsei Univ, Dept Comp Sci & Ind Syst Engn, Seodaemun Ku, Seoul 120749, South Korea
关键词
screening test; liver disease; growth curve; logistic regression; decision tree; neural network;
D O I
10.1016/j.biopha.2003.07.001
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
This study was done based on screening test data accumulated from 1994 to 2001 for studying of risk factor related with liver disease and prediction model of liver disease. In the existing study related with liver, the main current is studying on liver cancer, not on liver disease, previous step into liver cancer. As a result of estimating prediction model through the risk factors of liver disease and the growth curve on the basis of data, it is shown that most of the risk factors about liver disease are also those about known well as liver cancer. In addition, to investigate liver disease prevalence from the viewpoint of the future, this study presumed risk factor through the various growth curve analysis and examined logistic regression, decision tree and neural network from those estimators. In the case of neural network using growth curve estimator of X-t(5) = alpha(i) + beta(i)T + epsilon(iT), accuracy of liver disease was 72.55% and sensitivity was 78.62%. On the other hand, in the case of liver disease prediction model using recent screening test data estimator, accuracy was 72.09% and sensitivity was 71.72%. Those are lower than liver disease prediction model of growth curve analysis. In the various liver disease prediction models assumed by growth curve and many distinction models. when growth curve estimator was used, sensitivity value was improved. (C) 2003 Editions scientifiques et medicales Elsevier SAS. All rights reserved.
引用
收藏
页码:482 / 488
页数:7
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