An Orphan Nuclear Receptor Finds a Home

被引：10
|
作者：
Kimmel, Alan R. [1 ]
机构：
[1] NIDDKD, Cellular & Dev Biol Lab, NIH, Bethesda, MD 20892 USA
来源：
MOLECULAR CELL | 2010年 / 37卷 / 02期
关键词：
D O I：
10.1016/j.molcel.2010.01.008
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In this issue of Molecular Cell, Lee et al. (2010) show that the retinoic acid receptor-related orphan receptor alpha (ROR alpha) can suppress the Wnt/beta-catenin signaling pathway in a Wnt5a- and PKC-dependent manner that does not alter beta-catenin stabilization or the recruitment of beta-catenin to Wnt target promoters.
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页码：155 / 157
页数：3
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