Cryptococcosis as a cause of organizing pneumonia

被引：9

作者：

Chikumoto, Ayumi ^{[1
]}

Oishi, Keiji ^{[2
]}

Hamada, Kazuki ^{[1
]}

Matsuda, Kazuki ^{[1
]}

Uehara, Sho ^{[1
]}

Suetake, Ryo ^{[1
]}

Yamaji, Yoshikazu ^{[1
]}

Asami-Noyama, Maki ^{[1
]}

Edakuni, Nobutaka ^{[1
]}

Hirano, Tsunahiko ^{[1
]}

Murakami, Tomoyuki ^{[3
]}

Matsunaga, Kazuto ^{[1
]}

机构：

[1] Yamaguchi Univ, Grad Sch Med, Dept Resp Med & Infect Dis, 1-1-1 Minami Kogushi, Ube, Yamaguchi 7558505, Japan

[2] Yamaguchi Univ, Grad Sch Med, Dept Med & Clin Sci, 1-1-1 Minami Kogushi, Ube, Yamaguchi 7558505, Japan

[3] Natl Hosp Org, Kanmon Med Ctr, Dept Pathol, 1-1 Chofusotouracho, Shimonoseki, Yamaguchi 7528510, Japan

来源：

RESPIRATORY MEDICINE CASE REPORTS | 2019年 / 27卷

关键词：

Cryptococcosis; Organizing pneumonia; Immunocompromised host; Bronchoscopy; Serum cryptococcal antigen test; PULMONARY CRYPTOCOCCOSIS; CT FINDINGS; IMMUNOCOMPETENT;

D O I：

10.1016/j.rmcr.2019.100851

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

In cases showing organizing pneumonia (OP) with radiologic findings and pathological images, it is necessary to differentiate between idiopathic and secondary diseases as the cause of OP. Cryptococcus infection as a cause of OP is not well known. We herein report two cases of secondary pulmonary cryptococcosis in immunocompromised patients who showed OP, and the usefulness of bronchoscopy and serum cryptococcal antigen test for an early diagnosis. Common to both cases was that antibiotic therapy and corticosteroid therapy were ineffective, while antifungal agents were effective. In cases of immunocompromised patients who present OP with radiologic findings or pathological images, prompt administration of antifungal treatment at an early stage is important when pulmonary cryptococcosis is identified by bronchoscopy and serum cryptococcal antigen test.

引用

页数：5

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